Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA 19104-6392, USA.
Clin Sports Med. 2011 Jan;30(1):19-31, vii. doi: 10.1016/j.csm.2010.08.009.
The rising awareness of the long-term health problems associated with concussions re-emphasizes the need for understanding the mechanical etiology of concussions. This article reviews past studies defining the common mechanisms for mild traumatic brain injury and summarizes efforts to convert the external input to the head (force, acceleration, and velocity) into estimates of motions and deformations of the brain that occur during mild traumatic brain injury. Studies of how these mechanical conditions contribute to the cellular mechanisms of damage in mild traumatic brain injury are reviewed. Finally, future directions for improving understanding concussion biomechanics are discussed.
与脑震荡相关的长期健康问题的意识不断提高，这再次强调了需要了解脑震荡的机械病因。本文回顾了过去定义轻度创伤性脑损伤常见机制的研究，并总结了将头部受到的外力（力、加速度和速度）转换为轻度创伤性脑损伤期间大脑运动和变形估计值的努力。本文还回顾了这些机械条件如何导致轻度创伤性脑损伤中细胞损伤机制的研究。最后，讨论了改善对脑震荡生物力学理解的未来方向。
