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轻度创伤性脑损伤中的视觉功能障碍:聚焦调节系统损伤

Visual Dysfunctions in Mild Traumatic Brain Injury: A Focus on Accommodative System Impairments.

作者信息

Almutairi Nawaf M

机构信息

Department of Optometry, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.

出版信息

Life (Basel). 2025 May 6;15(5):744. doi: 10.3390/life15050744.

Abstract

: Mild traumatic brain injury (mTBI) is a prevalent neurological condition that results in various physical, emotional, and cognitive impairments. The most common are visual impairments, which affect vision's perceptual, motor, and sensory aspects. : This paper analyzes the pathophysiology of mild traumatic brain injury (mTBI) and its effects on visual and oculomotor functions, focusing on the deficits of the accommodative system and their underlying mechanism. : mTBI frequently causes diffuse axonal injury, resulting in abnormalities of the neurometabolic cascade that impact the brain's visual regions. Accommodative anomalies, including insufficiency, infacility, and spasm, are markedly more common in mTBI patients than in the general population. These deficiencies present as a notable delay in accommodation response, diminished peak velocity, and compromised dynamic responses, possibly due to sensory and motor disturbances. : Accommodation disorder is a significant but under-examined component of visual sequelae related to mTBI. Future research should concentrate on the sensory and motor factors contributing to these deficiencies to enhance diagnostic precision and customize rehabilitative strategies.

摘要

轻度创伤性脑损伤(mTBI)是一种常见的神经疾病,会导致各种身体、情感和认知障碍。最常见的是视觉障碍,它会影响视觉的感知、运动和感觉方面。本文分析了轻度创伤性脑损伤(mTBI)的病理生理学及其对视觉和眼球运动功能的影响,重点关注调节系统的缺陷及其潜在机制。mTBI经常导致弥漫性轴索损伤,导致神经代谢级联异常,影响大脑的视觉区域。调节异常,包括调节不足、调节困难和痉挛,在mTBI患者中明显比普通人群更常见。这些缺陷表现为调节反应明显延迟、峰值速度降低和动态反应受损,可能是由于感觉和运动障碍。调节障碍是与mTBI相关的视觉后遗症的一个重要但未得到充分研究的组成部分。未来的研究应集中在导致这些缺陷的感觉和运动因素上,以提高诊断精度并定制康复策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adb7/12113616/867aa636b95b/life-15-00744-g001.jpg

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