Department of Surgery, Division of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada.
J Arthroplasty. 2011 Sep;26(6):909-13. doi: 10.1016/j.arth.2010.08.014. Epub 2010 Nov 12.
Blood transfusion after joint arthroplasty occurs in up to two thirds of patients. We conducted a systematic review of the literature to determine the methodological quality of published randomized controlled trials (RCTs). We searched MEDLINE, EMBASE, and Cochrane to identify RCTs in arthroplasty with blood conservation as the primary outcome from 2001 to 2007. Methodological quality was evaluated using the Detsky index. We identified 62 RCTs. The mean Detsky score was 73% ± 14%. Epidemiology affiliation (P = .003), funding support (<.001), and year of publication (<.001) were the predictors of reporting quality, predicting 46% of the variability (R(2) = 0.46). This suggests poor reporting quality of trials in blood conservation. The inclusion of an epidemiologist or a biostatistician for the design of a trial is strongly recommended.
关节置换术后的输血发生率高达三分之二。我们对文献进行了系统性回顾，以确定已发表的随机对照试验（RCT）的方法学质量。我们检索了 MEDLINE、EMBASE 和 Cochrane，以确定在 2001 年至 2007 年间，以血液保护为主要结果的关节置换术的 RCT。使用 Detsky 指数评估方法学质量。我们确定了 62 项 RCT。平均 Detsky 得分为 73%±14%。流行病学背景（P=.003）、资金支持（<.001）和发表年份（<.001）是报告质量的预测因素，可预测 46%的变异性（R2=0.46）。这表明血液保护试验的报告质量较差。强烈建议在试验设计中纳入一名流行病学家或生物统计学家。
