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本文引用的文献

1
Designing a strategy to implement cost-effective blood transfusion management in elective hip and knee arthroplasties: a study protocol.设计一种策略,以实施髋关节和膝关节置换术择期手术中具有成本效益的输血管理:研究方案。
Implement Sci. 2012 Jun 30;7:58. doi: 10.1186/1748-5908-7-58.
2
A cost study of postoperative cell salvage in the setting of elective primary hip and knee arthroplasty.择期初次髋关节和膝关节置换术后应用细胞回收的成本研究。
Transfusion. 2012 Aug;52(8):1750-60. doi: 10.1111/j.1537-2995.2011.03531.x. Epub 2012 Feb 17.
3
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.氨甲环酸在全膝关节置换术中的应用:一项系统评价与荟萃分析。
J Bone Joint Surg Br. 2011 Dec;93(12):1577-85. doi: 10.1302/0301-620X.93B12.26989.
4
Risks of transfusion.输血风险
South Med J. 2011 Nov;104(11):762-9. doi: 10.1097/SMJ.0b013e31823213b6.
5
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.抗纤溶药物用于减少围手术期异体输血。
Cochrane Database Syst Rev. 2011 Mar 16;2011(3):CD001886. doi: 10.1002/14651858.CD001886.pub4.
6
Evaluating comorbidities in total hip and knee arthroplasty: available instruments.评估全髋关节和全膝关节置换术的合并症:可用的工具。
J Orthop Traumatol. 2010 Dec;11(4):203-9. doi: 10.1007/s10195-010-0115-x. Epub 2010 Nov 13.
7
Quality of assessment of randomized controlled trials in blood conservation after joint arthroplasty.关节置换术后血液保护中随机对照试验评估质量的评价。
J Arthroplasty. 2011 Sep;26(6):909-13. doi: 10.1016/j.arth.2010.08.014. Epub 2010 Nov 12.
8
Anemia and patient blood management in hip and knee surgery: a systematic review of the literature.髋关节和膝关节手术中的贫血和患者血液管理:文献系统评价。
Anesthesiology. 2010 Aug;113(2):482-95. doi: 10.1097/ALN.0b013e3181e08e97.
9
Cell salvage for minimising perioperative allogeneic blood transfusion.细胞回收技术用于减少围手术期异体输血。
Cochrane Database Syst Rev. 2010 Apr 14;2010(4):CD001888. doi: 10.1002/14651858.CD001888.pub4.
10
A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells.择期骨科手术中使用去白细胞红细胞时的输血触发因素的随机比较。
Vox Sang. 2010 Jan;98(1):56-64. doi: 10.1111/j.1423-0410.2009.01225.x. Epub 2009 Jul 23.

频繁使用血液保护措施在择期骨科手术中:2012 年荷兰血液管理调查。

Frequent use of blood-saving measures in elective orthopaedic surgery: a 2012 Dutch blood management survey.

机构信息

Department of Medical Decision Making, Leiden University Medical Center, Albinusdreef 2, Leiden 2333, ZA the Netherlands.

出版信息

BMC Musculoskelet Disord. 2013 Aug 5;14:230. doi: 10.1186/1471-2474-14-230.

DOI:10.1186/1471-2474-14-230
PMID:23915322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3750265/
Abstract

BACKGROUND

Blood loss in hip and knee arthroplasties may necessitate allogeneic blood transfusions. Different blood-saving measures (BSMs) were introduced to reduce these transfusions. Purpose of the present study was to assess the frequency of BSM use, stratified by type and hospital setting of orthopaedic departments in the Netherlands.

METHODS

An internet-based questionnaire was sent to all heads of orthopaedic departments of Dutch hospitals and private clinics (n = 99). Questions were asked on how often BSMs were used, reported on a 5-point Likert scale (never, almost never, regularly, almost always, always). In addition there were questions about discontinuation of anticoagulants preoperatively, the number of annually performed arthroplasties (size) and hospital setting.

RESULTS

The survey was completed by 81 (82%) departments. BSMs used frequently (regularly, almost always, always) were erythropoietine (EPO), with 55 (68%) departments being frequent users; acute normovolemic hemodilution, used frequently in 26 (32%) departments; cell saver in 25 (31%) and postoperative drainage and re-infusion in 56 (69%) departments. When compared by size, frequent EPO use was more common in large departments (with 22 (88%) large departments being frequent users versus 13 (63%) small departments and 16 (55%) intermediate departments, p = 0.03). No differences by size or type were observed for other BSMs.

CONCLUSIONS

Compared with previous survey's there is a tremendous increase in use of BSMs. EPO and autologous blood salvage techniques are the most often used modalities. Costs might be saved if use of non-cost-effective BSMs is stopped.

摘要

背景

髋关节和膝关节置换术可能需要异体输血。不同的血液保存措施(BSM)被引入以减少这些输血。本研究的目的是评估荷兰骨科部门的类型和医院设置对 BSM 使用频率的影响。

方法

我们向荷兰所有医院和私人诊所的骨科部门负责人发送了一份基于互联网的问卷(n=99)。问题是关于 BSM 的使用频率,回答采用 5 分制(从不、几乎从不、定期、几乎总是、总是)。此外,还询问了术前抗凝剂的停用情况、每年进行的关节置换术数量(规模)和医院设置。

结果

81 个(82%)部门完成了调查。经常使用(定期、几乎总是、总是)的 BSM 是促红细胞生成素(EPO),有 55 个(68%)部门是经常使用者;急性等容血液稀释,有 26 个(32%)部门经常使用;细胞保存器有 25 个(31%),术后引流和再输注有 56 个(69%)部门。按规模比较时,大型部门(22 个(88%)大型部门是经常使用者,而 13 个(63%)小型部门和 16 个(55%)中型部门)EPO 的使用频率更高(p=0.03)。其他 BSM 则没有发现规模或类型的差异。

结论

与以前的调查相比,BSM 的使用有了巨大的增加。EPO 和自体血液回收技术是最常用的方法。如果停止使用非成本效益的 BSM,可以节省成本。