van Oostrom Hugo, Schoemaker Nico J, Uilenreef Joost J
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, PO Box 80.154 NL-3508 TD Utrecht, The Netherlands.
Vet Clin North Am Exot Anim Pract. 2011 Jan;14(1):105-16. doi: 10.1016/j.cvex.2010.09.001.
The growing popularity of ferrets as pets has created the demand for advanced veterinary care for these patients. Pain is associated with a broad range of conditions, including acute or chronic inflammatory disease, neoplasia, and trauma, as well as iatrogenic causes, such as surgery and diagnostic procedures. Effective pain management requires knowledge and skills to assess pain, good understanding of the pathophysiology of pain, and general knowledge of pharmacologic and pharmacodynamic principles. Unfortunately, scientific studies on efficacy, pharmacokinetics, pharmacodynamics, and safety of analgesic drugs in the ferret are limited. However, basic rules on the treatment of pain and mechanisms of action, safety, and efficacy of analgesic drugs in other species can be adapted and applied to pain management in ferrets. This article aims to make an inventory of what is known on the recognition of pain in ferrets, what analgesic drugs are currently used in ferrets, and how they can be adopted in a patient-orientated pain management plan to provide effective pain relief while reducing and monitoring for unwanted side effects.
雪貂作为宠物越来越受欢迎，这就产生了对这些动物进行高级兽医护理的需求。疼痛与多种病症相关，包括急性或慢性炎症性疾病、肿瘤以及创伤，还有医源性原因，如手术和诊断程序。有效的疼痛管理需要评估疼痛的知识和技能、对疼痛病理生理学的深入理解以及药理学和药效学原理的一般知识。不幸的是，关于雪貂镇痛药的疗效、药代动力学、药效学和安全性的科学研究有限。然而，其他物种疼痛治疗的基本规则以及镇痛药的作用机制、安全性和疗效可以进行调整并应用于雪貂的疼痛管理。本文旨在梳理关于雪貂疼痛识别的已知情况、目前雪貂使用的镇痛药以及如何将它们纳入以患者为导向的疼痛管理计划，以提供有效的疼痛缓解，同时减少并监测不良副作用。
