[西班牙阿拉贡育龄妇女风疹血清流行病学研究（2003 - 2007年）]

[Seroepidemiologic study of rubella in childbearing women in Aragon, Spain (2003-2007)].

作者信息

Hernández Díaz Rogelio, Rodrigo Val María Pilar, Misiego Peral Antonio, Roc Alfaro María Lourdes, Adiego Sancho María Begoña

机构信息

Unidad Docente de Medicina Preventiva y Salud Pública de Aragón, Zaragoza, España.

出版信息

Gac Sanit. 2011 Jan-Feb;25(1):20-2. doi: 10.1016/j.gaceta.2010.09.003. Epub 2010 Nov 12.

DOI:10.1016/j.gaceta.2010.09.003

PMID:21074904

Abstract

OBJECTIVES

To quantify and identify the rubella-susceptible population in Aragon according to sociodemographic variables, with the aim of assessing compliance with the 5% limit set by the World Health Organization (WHO).

METHODS

Rubella serology tests performed in women of childbearing age in the Miguel Servet Hospital from 2003 to 2007 were studied. A descriptive analysis of seronegativity was performed by age, years of study, and WHO region (for 2007). A logistic regression was performed with the independent variables of age and geographical origin.

RESULTS

We studied 13,136 women. The mean age was 31.2 years. During the study period, 5% were susceptible to rubella (95%CI: 4.63-5.37). In 2003, 8.8% were seronegative and the highest percentage (12.3%) was found in women aged 15 to 19 years. The percentage of seronegativity was higher in foreign-born women (7.7%), especially those from Asia, than in Spanish women (3.3%; p<0.05).

CONCLUSIONS

Postpartum preventive strategies should be established to prevent possible rubella outbreaks and cases of congenital rubella syndrome.

摘要

目的

根据社会人口统计学变量对阿拉贡地区风疹易感人群进行量化和识别，以评估是否符合世界卫生组织（WHO）设定的5%的限制标准。

方法

对2003年至2007年在米格尔·塞尔维特医院进行的育龄妇女风疹血清学检测进行研究。按年龄、受教育年限和WHO地区（针对2007年）对血清阴性进行描述性分析。以年龄和地理来源为自变量进行逻辑回归分析。

结果

我们研究了13136名妇女。平均年龄为31.2岁。在研究期间，5%的人对风疹易感（95%CI：4.63 - 5.37）。2003年，8.8%的人血清阴性，15至19岁的女性中该比例最高（12.3%）。出生在国外的女性血清阴性比例更高（7.7%），尤其是来自亚洲的女性，高于西班牙女性（3.3%；p<0.05）。