Health Care Knowledge Centre, Brussels, Belgium.
Vaccine. 2011 Jan 10;29(3):370-7. doi: 10.1016/j.vaccine.2010.10.079. Epub 2010 Nov 12.
This European workshop identified a number of lessons learnt in the field of vaccine licensure, prioritization of target groups, communication on pandemic vaccines, implementation of vaccination and safety monitoring. The mild severity of the pandemic A(H1N1) 2009 influenza virus influenced the perception of pandemic vaccines, as previous pandemic preparedness had anticipated a more virulent virus. This vaccination experience provides an important opportunity for research on the long-term immunogenicity and safety of pandemic vaccines in pregnant women and children, as well as on the long-term safety of adjuvants. Preparedness for future pandemics could involve improved decision-making on target groups and increased communication on vaccine safety.
本次欧洲研讨会确定了疫苗许可、目标人群优先级划分、大流行疫苗沟通、疫苗接种实施和安全性监测等领域的一些经验教训。大流行流感病毒 A(H1N1)2009 的轻度严重程度影响了对大流行疫苗的看法，因为此前的大流行准备工作预计会出现更具毒性的病毒。这次接种疫苗的经验为研究大流行疫苗在孕妇和儿童中的长期免疫原性和安全性以及佐剂的长期安全性提供了重要机会。未来大流行的准备工作可能涉及改进目标人群的决策制定和加强疫苗安全性沟通。
