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撒哈拉以南非洲老年人中的 HIV 感染:从现有数据推断流行率。

HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data.

机构信息

University of Sydney, School of Public Health, Edward Ford Building, Sydney, NSW, 2006, Australia.

出版信息

Bull World Health Organ. 2010 Nov 1;88(11):847-53. doi: 10.2471/BLT.10.076349. Epub 2010 Aug 27.

Abstract

OBJECTIVE

To quantify the number of cases and prevalence of human immunodeficiency virus (HIV) infection among older adults in sub-Saharan Africa.

METHODS

We reviewed data from Demographic and Health Surveys (DHS). Although in these surveys all female respondents are < 50 years of age, 18 of the surveys contained data on HIV infection among men aged ≥ 50 years. To estimate the percentage of older adults (i.e. people ≥ 50 years of age) who were positive for HIV (HIV+), we extrapolated from data from the Joint United Nations Programme on HIV/AIDS on the estimated number of people living with HIV and on HIV infection prevalence among adults aged 15-49 years.

FINDINGS

In 2007, approximately 3 million people aged ≥ 50 years were living with HIV in sub-Saharan Africa. The prevalence of HIV infection in this group was 4.0%, compared with 5.0% among those aged 15-49 years. Of the approximately 21 million people in sub-Saharan Africa aged ≥ 15 years that were HIV+, 14.3% were ≥ 50 years old.

CONCLUSION

To better reflect the longer survival of people living with HIV and the ageing of the HIV+ population, indicators of the prevalence of HIV infection should be expanded to include people > 49 years of age. Little is known about comorbidity and sexual behaviour among HIV+ older adults or about the biological and cultural factors that increase the risk of transmission. HIV services need to be better targeted to respond to the growing needs of older adults living with HIV.

摘要

目的

定量评估撒哈拉以南非洲老年人群体中人类免疫缺陷病毒(HIV)感染的病例数和流行率。

方法

我们回顾了来自人口与健康调查(DHS)的数据。尽管在这些调查中,所有女性受访者的年龄均<50 岁,但有 18 项调查包含了年龄≥50 岁男性中 HIV 感染的数据。为了估计 HIV 阳性(HIV+)的老年人群体(即年龄≥50 岁的人群)的百分比,我们从联合国艾滋病规划署(UNAIDS)的数据中推断出估计的 HIV 感染者人数以及 15-49 岁成年人中的 HIV 感染流行率。

结果

2007 年,撒哈拉以南非洲约有 300 万年龄≥50 岁的人携带 HIV。该年龄段 HIV 感染的流行率为 4.0%,而 15-49 岁年龄段的流行率为 5.0%。在撒哈拉以南非洲约 2100 万年龄≥15 岁的 HIV 感染者中,有 14.3%的年龄≥50 岁。

结论

为了更好地反映 HIV 感染者的生存时间延长和 HIV+人群的老龄化,HIV 感染流行率的指标应扩大到包括年龄>49 岁的人群。目前对于 HIV 阳性的老年人群体的合并症和性行为,以及增加传播风险的生物学和文化因素知之甚少。HIV 服务需要更好地针对满足 HIV 阳性老年人群体不断增长的需求。

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