Klöppel S
Neurozentrum, Freiburg Brain Imaging, Zentrum für Geriatrie und Gerontologie, Abteilung für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Hauptstraße 5, 79104, Freiburg.
Nervenarzt. 2010 Dec;81(12):1456-9. doi: 10.1007/s00115-010-3104-7.
Dementia is underdiagnosed and undertreated in Germany. Automatic diagnosing of dementia based on standard magnetic resonance imaging has the capacity to reduce diagnostic uncertainties. The algorithm learns a disease specific pattern of atrophy from training samples. It is independent from radiological expertise which may be scarce outside specialised centres and can be installed on MRT-machines or desktop PCs. It can also play its part in planning and conducting treatment trials by recruiting a sample with predicted fast future decline. Extension, based e.g. on resting state functional imaging are possible but are further away from clinical routine.