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单肺通气时非通气侧肺血流的变化。

The changes of pulmonary blood flow in non-ventilated lung during one lung ventilation.

机构信息

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.

出版信息

J Clin Monit Comput. 2010 Dec;24(6):407-12. doi: 10.1007/s10877-010-9262-0. Epub 2010 Nov 13.

DOI:10.1007/s10877-010-9262-0
PMID:21076859
Abstract

OBJECTIVE

A pulmonary artery catheter placement is necessary for intrapulmonary shunt fraction evaluation. The purpose of this study was to investigate the feasibility for detecting the changes of regional pulmonary blood flow in non-ventilated lung by transesophageal echocardiography (TEE) during one-lung ventilation (OLV).

METHODS

22 adult patients for selective thoracic surgery were enrolled in the study. Doppler flow patterns in left upper pulmonary vein (LUPV) were obtained by TEE before switching to right OLV and every 5 min in 30 min OLV period. Systolic peak velocity (Vs), diastolic peak velocity (Vd) and velocity time integral (VTI) were measured respectively.

RESULTS

The VTI of LUPV blood flow pattern decreased significantly 5 min after right OLV. The percent of changes in LUPV blood flow decreased rapidly by 78.4 and 67.7% at OLV 5 min and 10 min, respectively. Then it slowly decreased by 60% at OLV 30 min.

CONCLUSIONS

Provides an alternative method to measure the changes of pulmonary blood flow during OLV. The percent changes of regional pulmonary blood flow decreased immediately after OLV, and decreased by 60% at 30 min OLV.

摘要

目的

肺动脉导管放置对于评估肺内分流量是必要的。本研究旨在探讨经食管超声心动图(TEE)在单肺通气(OLV)期间检测非通气肺区肺血流变化的可行性。

方法

本研究纳入了 22 例择期行胸部手术的成年患者。在切换至右侧 OLV 前和 OLV 30 分钟期间的每 5 分钟,通过 TEE 获得左上肺静脉(LUPV)的多普勒血流模式。分别测量收缩峰速度(Vs)、舒张峰速度(Vd)和速度时间积分(VTI)。

结果

右侧 OLV 5 分钟后,LUPV 血流模式的 VTI 显著降低。LUPV 血流的变化百分比在 OLV 5 分钟和 10 分钟时分别迅速下降了 78.4%和 67.7%,然后在 OLV 30 分钟时缓慢下降了 60%。

结论

为测量 OLV 期间肺血流变化提供了一种替代方法。OLV 后,区域性肺血流的变化百分比立即下降,在 30 分钟 OLV 时下降 60%。

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Automated measurement and classification of pulmonary blood-flow velocity patterns using phase-contrast MRI and correlation analysis.使用相位对比磁共振成像和相关分析对肺血流速度模式进行自动测量和分类。
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Physiological effects of a lung-recruiting strategy applied during one-lung ventilation.单肺通气期间应用肺复张策略的生理效应。
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A new method to estimate regional pulmonary blood flow using transesophageal echocardiography.
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Echocardiographic evaluation of pulmonary venous blood flow and cardiac function changes during one-lung ventilation.单肺通气期间肺静脉血流及心功能变化的超声心动图评估
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Flurbiprofen axetil increases arterial oxygen partial pressure by decreasing intrapulmonary shunt in patients undergoing one-lung ventilation.氟比洛芬酯通过减少单肺通气患者的肺内分流来提高动脉血氧分压。
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J Clin Monit Comput. 2015 Apr;29(2):307-11. doi: 10.1007/s10877-014-9606-2.
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Arterial oxygenation during one-lung ventilation may not improve within 30 min.单肺通气期间的动脉氧合在30分钟内可能无法改善。
J Clin Monit Comput. 2011 Apr;25(2):143-4. doi: 10.1007/s10877-011-9272-6. Epub 2011 Feb 16.
一种使用经食管超声心动图估计局部肺血流量的新方法。
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