• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肉毒杆菌毒素注射治疗痉挛性发声障碍后的语音相关生活质量

Voice related quality of life after botulinum toxin injection for spasmodic dysphonia.

作者信息

Gama A C C, Menezes L N, Maia A A, Rezende Neto A L, Oliveira J B

机构信息

Department of the Federal University of Minas Gerais, Rua Luiz Fernando 47, Santa Mônica, 31530-630 Belo Horizonte, Minas Gerais, Brazil.

出版信息

Rev Laryngol Otol Rhinol (Bord). 2010;131(1):39-44.

PMID:21077414
Abstract

INTRODUCTION

Laryngeal Focal Dystonia (LFD) leads to a type of voice with a strained and tense quality which has a neurological origin, affecting the social-emotional realms of the individuals, and their quality of life.

AIMS

Measure the voice-related quality of life of patients with Adductor LFD pre and post-treatment with Botox, injection followed by voice therapy, using the Voice-Related Quality of Life (V-RQOL).

STUDY DESIGN

Prospective study.

METHODS

Adductor 11 female patients aged between 33 and 74 years with a diagnosis of Adductor LFD were evaluated. All patients underwent a neurological evaluation. Laryngoscopy was performed with both rigid and flexible endoscopes. Speech and Language evaluation followed the Evaluation of Voice Protocol, proposed by Behlau, Pontes (1995). The American V-RQOL measure was utilized.

RESULTS

Statistical analysis demonstrated significant difference (p < 0.05). 81.8% of patients showed higher scores post-Botox, for the social-emotional and physical domain. In the overall V-RQOL scores 72.7% of patients showed greater scores post-treatment.

CONCLUSIONS

There was an improvement in the quality of life for these patients post-treatment. The V-RQOL proved to be an efficient tool to measure the treatment outcomes of LFD pre and post botulinum toxin injection.

摘要

引言

喉肌张力障碍(LFD)会导致一种声音紧张、紧绷的嗓音,其病因源于神经方面,会影响个体的社会情感领域及其生活质量。

目的

使用与嗓音相关的生活质量(V-RQOL)量表,测量肉毒杆菌毒素注射联合嗓音治疗前后内收型LFD患者与嗓音相关的生活质量。

研究设计

前瞻性研究。

方法

对11名年龄在33至74岁之间、诊断为内收型LFD的女性患者进行评估。所有患者均接受了神经学评估。使用硬性和软性内窥镜进行喉镜检查。言语和语言评估遵循Behlau、Pontes(1995年)提出的嗓音评估方案。采用美国的V-RQOL量表。

结果

统计分析显示存在显著差异(p < 0.05)。81.8%的患者在接受肉毒杆菌毒素治疗后,在社会情感和身体领域的得分更高。在总体V-RQOL得分方面,72.7%的患者在治疗后得分更高。

结论

这些患者治疗后的生活质量有所改善。V-RQOL量表被证明是一种测量肉毒杆菌毒素注射前后LFD治疗效果的有效工具。

相似文献

1
Voice related quality of life after botulinum toxin injection for spasmodic dysphonia.肉毒杆菌毒素注射治疗痉挛性发声障碍后的语音相关生活质量
Rev Laryngol Otol Rhinol (Bord). 2010;131(1):39-44.
2
A comparison of the VHI, VHI-10, and V-RQOL for measuring the effect of botox therapy in adductor spasmodic dysphonia.比较 VHI、VHI-10 和 V-RQOL 在评估肉毒毒素治疗内收肌痉挛性发音障碍中的疗效。
J Voice. 2012 May;26(3):378-80. doi: 10.1016/j.jvoice.2010.07.011. Epub 2010 Oct 16.
3
Longitudinal effects of botulinum toxin injections on voice-related quality of life (V-RQOL) for patients with adductory spasmodic dysphonia.肉毒杆菌毒素注射对内收性痉挛性发声障碍患者嗓音相关生活质量(V-RQOL)的纵向影响。
J Voice. 2001 Dec;15(4):576-86. doi: 10.1016/S0892-1997(01)00060-1.
4
Botulinum toxin treatment of adductor spasmodic dysphonia: longitudinal functional outcomes.肉毒毒素治疗内收肌痉挛性发音障碍:纵向功能结局。
Laryngoscope. 2011 Mar;121(3):606-12. doi: 10.1002/lary.21395. Epub 2011 Feb 4.
5
Combined modality treatment of adductor spasmodic dysphonia.联合治疗内收肌痉挛性发音障碍。
J Voice. 2012 Jan;26(1):77-86. doi: 10.1016/j.jvoice.2010.08.004. Epub 2011 Feb 3.
6
Clinical practice guideline: hoarseness (dysphonia).临床实践指南:声音嘶哑(发音困难)。
Otolaryngol Head Neck Surg. 2009 Sep;141(3 Suppl 2):S1-S31. doi: 10.1016/j.otohns.2009.06.744.
7
Assessing the effectiveness of botulinum toxin injections for adductor spasmodic dysphonia: clinician and patient perception.评估肉毒杆菌毒素注射治疗内收肌痉挛性发音障碍的效果:临床医生和患者的感知。
J Voice. 2010 Mar;24(2):242-9. doi: 10.1016/j.jvoice.2008.08.003. Epub 2009 May 28.
8
Considerations for initial dosing of botulinum toxin in treatment of adductor spasmodic dysphonia.考虑在治疗内收肌痉挛性发音障碍时初次使用肉毒毒素的剂量。
Otolaryngol Head Neck Surg. 2013 Jun;148(6):1003-6. doi: 10.1177/0194599813484685. Epub 2013 Mar 27.
9
Longitudinal effects of Botox injections on voice-related quality of life (V-RQOL) for patients with adductory spasmodic dysphonia: part II.肉毒杆菌毒素注射对内收性痉挛性发音障碍患者嗓音相关生活质量(V-RQOL)的纵向影响:第二部分。
Arch Otolaryngol Head Neck Surg. 2004 Apr;130(4):415-20. doi: 10.1001/archotol.130.4.415.
10
Nonpharmacologic effects of botulinum toxin on the life quality of patients with spasmodic dysphonia.肉毒杆菌毒素对痉挛性发音障碍患者生活质量的非药物作用
Laryngoscope. 2007 Oct;117(10):1888-92. doi: 10.1097/MLG.0b013e3180de4d63.

引用本文的文献

1
Retrospective review of dosing trends in botulinum toxin injections for the treatment of adductor spasmodic dysphonia in a long-term cohort.回顾性分析长期队列中肉毒毒素注射治疗内收肌痉挛性发音障碍的剂量趋势。
J Otolaryngol Head Neck Surg. 2020 Jan 14;49(1):4. doi: 10.1186/s40463-020-0401-4.
2
Quality of life in idiopathic dystonia: a systematic review.特发性肌张力障碍患者的生活质量:系统评价。
J Neurol. 2019 Dec;266(12):2897-2906. doi: 10.1007/s00415-018-9119-x. Epub 2018 Nov 20.
3
Brief considerations on the dispensation profile of the botulinum toxin type A by the Brazilian Unified Health System for treatment of dystonias: Datasus data.
巴西统一卫生系统使用A型肉毒杆菌毒素治疗肌张力障碍的配药情况简述:巴西卫生部信息技术司数据
eNeurologicalSci. 2016 Jul 19;5:11-14. doi: 10.1016/j.ensci.2016.07.001. eCollection 2016 Dec.
4
Predictors of Six-month Change in the Voice Handicap Index in a Treatment-seeking Population.寻求治疗人群中嗓音障碍指数六个月变化的预测因素
J Voice. 2017 Jan;31(1):41-47. doi: 10.1016/j.jvoice.2016.02.004. Epub 2016 Mar 4.