Department of Medicine, University of Calgary, Calgary, AB, Canada.
Ther Adv Respir Dis. 2011 Apr;5(2):105-19. doi: 10.1177/1753465810386051. Epub 2010 Nov 15.
Improvements in the quality and implementation of medical care for individuals with cystic fibrosis (CF) have resulted in a dramatic improvement in survival. Many of these strategies have focused on the effective management of pulmonary disease which has delayed its manifestations into later years. With an increasing number of patients surviving to later years the impact of chronic inflammation and nutritional compromise on other organ systems over a lifetime are increasingly manifest. This review highlights the changing epidemiology of the ageing CF population and the complications that may ensue.
提高囊性纤维化（CF）患者的医疗质量和实施水平，显著改善了患者的生存率。这些策略中的许多都集中在肺病的有效管理上，从而将其发病时间推迟到了晚年。随着越来越多的患者能够存活到晚年，慢性炎症和营养失调对其他器官系统的终生影响也越来越明显。本综述强调了老龄化 CF 人群的不断变化的流行病学特征以及可能随之而来的并发症。
