Department of Nuclear Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
J Nucl Med. 2010 Dec;51(12):1937-49. doi: 10.2967/jnumed.110.076232. Epub 2010 Nov 15.
Nuclear medicine imaging procedures play an important role in the assessment of inflammatory diseases. With the advent of 3-dimensional anatomic imaging, there has been a tendency to replace traditional planar scintigraphy by CT or MRI. Furthermore, scintigraphic techniques may have to be combined with other imaging modalities to achieve high sensitivity and specificity, and some may require time-consuming labeling procedures. On the other hand, new developments such as combined SPECT/CT increase the diagnostic power of scintigraphy. Also, the advent of PET had a considerable impact on the use of nuclear medicine imaging techniques. In this review, we aim to provide nuclear medicine specialists and clinicians with the relevant information on rational and efficient use of nuclear medicine imaging techniques in the assessment of patients with osteomyelitis, infected vascular prostheses, metastatic infectious disease, rheumatoid arthritis, vasculitis, inflammatory bowel disease, sarcoidosis, and fever of unknown origin.
核医学成像在炎症性疾病的评估中起着重要作用。随着三维解剖成像的出现，传统的平面闪烁照相术有被 CT 或 MRI 取代的趋势。此外，闪烁照相技术可能需要与其他成像方式相结合，以达到高灵敏度和特异性，其中一些可能需要耗时的标记程序。另一方面，如 SPECT/CT 组合等新进展提高了闪烁照相术的诊断能力。此外，PET 的出现对核医学成像技术的应用也产生了相当大的影响。在这篇综述中，我们旨在为核医学专家和临床医生提供相关信息，以帮助他们合理有效地使用核医学成像技术来评估骨髓炎、感染性血管假体、转移性感染性疾病、类风湿关节炎、血管炎、炎症性肠病、结节病和不明原因发热的患者。
