Gotthardt Martin, Bleeker-Rovers Chantal P, Boerman Otto C, Oyen Wim J G
Department of Nuclear Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
J Nucl Med Technol. 2013 Sep;41(3):157-69. doi: 10.2967/jnumed.110.076232. Epub 2013 Aug 8.
Nuclear medicine imaging procedures play an important role in the assessment of inflammatory diseases. With the advent of 3-dimensional anatomic imaging, there has been a tendency to replace traditional planar scintigraphy by CT or MRI. Furthermore, scintigraphic techniques may have to be combined with other imaging modalities to achieve high sensitivity and specificity, and some may require time-consuming labeling procedures. On the other hand, new developments such as combined SPECT/CT increase the diagnostic power of scintigraphy. Also, the advent of PET had a considerable impact on the use of nuclear medicine imaging techniques. In this review, we aim to provide nuclear medicine specialists and clinicians with the relevant information on rational and efficient use of nuclear medicine imaging techniques in the assessment of patients with osteomyelitis, infected vascular prostheses, metastatic infectious disease, rheumatoid arthritis, vasculitis, inflammatory bowel disease, sarcoidosis, and fever of unknown origin.
核医学成像程序在炎症性疾病的评估中发挥着重要作用。随着三维解剖成像的出现，有一种用CT或MRI取代传统平面闪烁显像的趋势。此外，闪烁显像技术可能必须与其他成像方式相结合以实现高灵敏度和特异性，并且有些可能需要耗时的标记程序。另一方面，诸如SPECT/CT联合等新进展提高了闪烁显像的诊断能力。此外，PET的出现对核医学成像技术的应用产生了相当大的影响。在本综述中，我们旨在为核医学专家和临床医生提供有关在评估骨髓炎、感染性血管假体、转移性感染性疾病、类风湿关节炎、血管炎、炎症性肠病、结节病和不明原因发热患者时合理有效使用核医学成像技术的相关信息。
