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1000 厘沲硅油与重硅油作为伴有近视性黄斑裂孔的视网膜脱离眼内填充物的比较。

1000 cSt silicone oil vs heavy silicone oil as intraocular tamponade in retinal detachment associated to myopic macular hole.

机构信息

Department of Ophthalmology, Ospedale Sacro Cuore - Don Calabria, Via don A. Sempreboni 5, 37024, Negrar, VR, Italy.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2011 Jun;249(6):821-6. doi: 10.1007/s00417-010-1557-9. Epub 2010 Nov 16.

Abstract

BACKGROUND

Several surgical techniques have been described for the treatment of retinal detachment (RD) associated to myopic macular hole (MMH). In this retrospective study, the anatomical and functional outcomes of pars plana vitrectomy (PPV) with long-term tamponade, using either 1000 cSt silicone oil (SO) or heavy silicone oil (HSO), are compared.

METHODS

Forty-two eyes affected by RD associated with MMH were included. The surgical technique involved standard 3-port 20-gauge PPV with long-term tamponade. The patients were divided into two groups, according to the intraocular tamponade: SO in group 1 (n = 17), and HSO in group 2 (n = 25). Internal limiting membrane (ILM) removal was performed in 15 cases of group 1 and 20 cases of group 2. Tamponade removal was performed 2 to 5 months after primary surgery. The patients were assessed 1 week and 1 month after primary surgery, and then 1 week and 1 month after tamponade removal or after further surgery if macular redetachment had occurred. The patients were also visited every 2 months for at least 1 year after final tamponade removal. Follow-up was considered closed at 1 year after final tamponade removal.

RESULTS

Preoperative best-corrected visual acuity (BCVA), expressed as LogMar, was 2.8 ± 0.77 for group 1 and 2.1 ± 0.94 for group 2. At the last visit, the BCVA was 1.41 ± 0.96 and 1.48 ± 0.77 for groups 1 and 2 respectively. Retinal reattachment was achieved with one operation in 13 eyes of group 1 (76.5%) and 18 of group 2 (81.8%) (P = 0.69). The average number of surgery needed to achieve retinal attachment by patients of group 1 and 2 was respectively 1.36 ± 0.63 and 1.46 ± 0.59 (P = 0.77). Five patients of group 1 and four of group 2 developed a chronic glaucoma (P = 0.238).

CONCLUSIONS

PPV with ILM peeling and long-term tamponade was demonstrated to be a good surgical option to treat RD due to MMH; SO and HSO seemed to be equally effective, although the success rates remained far from an ideal 100%.

摘要

背景

几种手术技术已被描述用于治疗与近视性黄斑孔(MMH)相关的视网膜脱离(RD)。在这项回顾性研究中,比较了使用 1000 cSt 硅油(SO)或重硅油(HSO)进行长期眼内填塞的玻璃体切除术(PPV)的解剖和功能结果。

方法

纳入 42 只受 RD 合并 MMH 影响的眼睛。手术技术涉及标准的 3 端口 20 号auge PPV 联合长期眼内填塞。根据眼内填塞情况将患者分为两组:SO 组(n=17)和 HSO 组(n=25)。15 例 1 组和 20 例 2 组行内界膜(ILM)切除。初次手术后 2-5 个月取出眼内填塞。初次手术后 1 周和 1 个月、眼内填塞取出后或再次出现黄斑脱离后 1 周和 1 个月对患者进行评估。最后眼内填塞取出后至少 1 年,每 2 个月随访一次。最后眼内填塞取出后 1 年随访结束时认为随访结束。

结果

术前最佳矫正视力(BCVA),用 LogMar 表示,1 组为 2.8±0.77,2 组为 2.1±0.94。末次随访时,1 组 BCVA 为 1.41±0.96,2 组为 1.48±0.77。1 组 13 只眼(76.5%)和 2 组 18 只眼(81.8%)一次手术即可获得视网膜复位(P=0.69)。1 组和 2 组患者平均需要 1.36±0.63 次和 1.46±0.59 次手术才能获得视网膜附着(P=0.77)。1 组 5 例和 2 组 4 例发生慢性青光眼(P=0.238)。

结论

PPV 联合 ILM 剥除和长期眼内填塞被证明是治疗 MMH 引起的 RD 的一种良好手术选择;SO 和 HSO 似乎同样有效,尽管成功率远未达到理想的 100%。

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