南极假丝酵母脂肪酶 B 的突变变体在（S）-选择性动态动力学拆分仲醇中的应用。
Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols.
机构信息
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91, Stockholm, Sweden.
出版信息
Org Biomol Chem. 2011 Jan 7;9(1):81-2. doi: 10.1039/c0ob00748j. Epub 2010 Nov 17.
PMID:21082131
Abstract
An (S)-selective dynamic kinetic resolution of secondary alcohols, employing a mutated variant of Candida antarctica lipase B (CalB) gave products in 84-88% yield and in 90-97% ee.
摘要
采用突变型南极假丝酵母脂肪酶 B（CalB）对仲醇进行（S）-选择性动态动力学拆分，以 84%-88%的收率和 90%-97%的对映选择性得到产物。
Zotero 插件