O'Donovan Claire, Apweiler Rolf
The European Bioinformatics Institute, Cambridge, UK.
Methods Mol Biol. 2011;694:25-35. doi: 10.1007/978-1-60761-977-2_2.
One of the essential requirements of the proteomics community is a high quality annotated nonredundant protein sequence database with stable identifiers and an archival service to enable protein identification and characterization. The scope of this chapter is to illustrate how Universal Protein Resource (UniProt) (The UniProt Consortium, Nucleic Acids Res. 38:D142-D148, 2010) can be best utilized for proteomics purposes with a particular focus on exploiting the knowledge captured in the UniProt databases, the services provided and the availability of complete proteomes.
蛋白质组学领域的一项基本要求是拥有一个高质量的、带有稳定标识符的注释非冗余蛋白质序列数据库，以及一项存档服务，以实现蛋白质的鉴定和表征。本章的范围是说明如何将通用蛋白质资源（UniProt）（UniProt联盟，《核酸研究》38：D142 - D148，2010年）最佳地用于蛋白质组学目的，特别着重于利用UniProt数据库中所包含的知识、所提供的服务以及完整蛋白质组的可用性。
