Mavrogenis Andreas F, Papagelopoulos Panayiotis J, Romantini Matteo, Guerra Giovanni, Ruggieri Pietro
First Department of Orthopaedics, Athens University Medical School, Athens Greece.
J Long Term Eff Med Implants. 2009;19(4):287-304. doi: 10.1615/jlongtermeffmedimplants.v19.i4.60.
Radiation therapy is applied for systemic effects to patients with bone and soft tissue tumors and for local effects that facilitate the surgical procedure. However, while it remains an essential treatment of cancers, radiation therapy is associated with unwanted complications. The purpose of this review is to summarize information regarding the complications of radiation in musculoskeletal oncology and their management. Because preoperative radiotherapy is associated with an increased risk of wound complications and postoperative radiation is associated with an increased risk of postradiation fractures, the physician requires additional information in deciding on the best method of treatment, and such information is provided in this review.
放射治疗应用于骨与软组织肿瘤患者的全身效应以及促进手术操作的局部效应。然而，尽管放射治疗仍是癌症的重要治疗手段，但它会引发不良并发症。本综述的目的是总结有关肌肉骨骼肿瘤放射治疗并发症及其管理的信息。由于术前放疗会增加伤口并发症的风险，术后放疗会增加放射后骨折的风险，医生在决定最佳治疗方法时需要更多信息，而本综述提供了此类信息。
