Dermatology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
J Cutan Med Surg. 2010 Nov-Dec;14(6):303-6. doi: 10.2310/7750.2010.09070.
Cutaneous leishmaniasis can lead to unsightly atrophic scars, which have limited treatment options. There is a scarcity of literature on its treatment modalities. Fractional lasers have been successfully used in treating a variety of skin conditions with minimal downtime and side effects.
We report a successful treatment of a 25-year-old female patient with an atrophic scar from cutaneous leishmaniasis on the nose with a fractional laser (Fraxel Re:store SR 1500). Ten treatment sessions were performed at a pulse energy of 45 to 70 mJ. The treatment response was assessed by comparing pre- and posttreatment clinical photographs.
After three sessions, the patient observed 40% improvement. More than 90% improvement was noticed after the tenth session. No significant adverse effects were noted. The improvement was persistent at the 3-month follow-up.
The excellent improvement in this patient should encourage further studies to achieve more efficacy and optimize the treatment parameters.
皮肤利什曼病可导致难看的萎缩性瘢痕，其治疗选择有限。关于其治疗方式的文献很少。分束激光已成功用于治疗多种皮肤疾病，具有最小的停机时间和副作用。
我们报告了一例成功治疗 25 岁女性患者鼻部皮肤利什曼病所致萎缩性瘢痕的病例，该患者采用分束激光（Fraxel Re:store SR 1500）治疗。以 45 至 70 mJ 的脉冲能量进行了 10 次治疗。通过比较治疗前后的临床照片评估治疗反应。
三次治疗后，患者观察到 40%的改善。第十次治疗后，改善超过 90%。未观察到明显的不良反应。在 3 个月的随访中，改善仍持续存在。
该患者的显著改善应鼓励进一步研究以获得更高的疗效并优化治疗参数。
