Nilforoushzadeh Mohammad Ali, Minaravesh Shahriar, Jaffary Fariba, Siadat Amir Hossein, Haftbaradaran Elaheh
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
General Physician, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2014 Dec 31;3:259. doi: 10.4103/2277-9175.148231. eCollection 2014.
The aim of this study is to compare ablative CO2 laser with fractional CO2 laser on healing of the wound and the size of cutaneous leishmaniasis scars.
This prospective randomized clinical trial study was done on 120 patients in two groups evaluated in Sedigheh Tahereh Hospital in Isfahan. The patients in case group underwent one session ablative CO2 laser for treatment of leishmaniasis scars and the patients in control group underwent six 3-weeks interval sessions fractional CO2 laser for treatment of leishmaniasis scars. All cases were evaluated from size and other aspects of scar by a questionnaire, and before and 6 months after photos were evaluated by blinded dermatologist. The data collected in the check list was then analyzed by t-test and Chi-square with SPSS 20.
There were 60 people in case group and 60 in control group. The mean age was 27.21 ± 11.2. Our results show that fractional CO2 laser is better than ablative CO2 laser in various aspect of treatment of leishmaniasis scars (P < 0.05).
Fractional CO2 laser is better than ablative CO2 laser in variants aspect of treatment of leishmaniasis scars.
本研究旨在比较剥脱性二氧化碳激光与非剥脱性二氧化碳激光对伤口愈合及皮肤利什曼病瘢痕大小的影响。
这项前瞻性随机临床试验研究在伊斯法罕的塞迪盖赫·塔赫雷医院对120例患者进行了两组评估。病例组患者接受一次剥脱性二氧化碳激光治疗利什曼病瘢痕，对照组患者接受六次间隔3周的非剥脱性二氧化碳激光治疗利什曼病瘢痕。所有病例通过问卷从瘢痕大小和其他方面进行评估，由盲法皮肤科医生评估治疗前和治疗后6个月的照片。然后使用SPSS 20对检查表中收集的数据进行t检验和卡方检验分析。
病例组60人，对照组60人。平均年龄为27.21±11.2。我们的结果表明，在治疗皮肤利什曼病瘢痕的各个方面，非剥脱性二氧化碳激光优于剥脱性二氧化碳激光（P<0.05）。
在治疗皮肤利什曼病瘢痕的不同方面，非剥脱性二氧化碳激光优于剥脱性二氧化碳激光。
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