Schweiger Eric S, Sundick Lauren
J Drugs Dermatol. 2013 Oct;12(10):1163-7.
Acne scars are a common concern in dermatology. Fractional CO2 laser resurfacing is a recent addition in our armamentarium of treatment options for acne scars and has been shown to be an excellent option for patients with atrophic acne scars. Patients with acne scars receiving fractional CO2 resurfacing usually have both the acne scars and surrounding unscarred areas treated in common practice. There has yet to be a study that looked at the implications of only focally treating the acne scars while leaving surrounding normal skin untreated.
To evaluate the safety and efficacy of a focal approach to fractional CO2 laser treatment for acne scars, coined "Focal Acne Scar Treatment" or "FAST"
This retrospective case series was conducted at Schweiger Dermatology, in New York, NY, with patients treated from November 2011 through May 2012. Overall, six patients (ages 18 to 48) were treated with the fractional CO2 laser resurfacing, using a so called "FAST" technique treating only the acne scars and leaving normal skin untreated. Evaluation was based on physician and patient assessment of improvement at one week and four weeks post-treatment.
All six patients treated with the Focal Acne Scar Treatment technique of fractional CO2 laser resurfacing had significant improvement post treatment ranging from 40% to 70% as estimated by the treating dermatologist and patient at four weeks post treatment. Patient satisfaction was high following FAST method. Temporary post-inflammatory hyperpigmentation was seen in two patients but resolved after a single 1550 nm Erbium Glass fractional laser treatment.
The Focal Acne Scar Treatment technique is an effective method of improving the appearance of atrophic acne scars. Higher energy and density levels can be used when utilizing this technique, resulting in improved outcomes when compared with whole face fractional CO2 laser resurfacing. Healing is improved and faster with this technique and no increased incidence of permanent adverse events were found. More studies are needed to further evaluate this new technique.
痤疮瘢痕是皮肤科常见的问题。分次二氧化碳激光换肤术是我们治疗痤疮瘢痕的一系列治疗选择中的最新方法，已被证明是治疗萎缩性痤疮瘢痕患者的极佳选择。在常规治疗中，接受分次二氧化碳换肤术治疗痤疮瘢痕的患者通常痤疮瘢痕和周围未瘢痕化区域都接受治疗。尚未有研究探讨仅局部治疗痤疮瘢痕而不治疗周围正常皮肤的影响。
评估一种用于痤疮瘢痕的分次二氧化碳激光局部治疗方法（称为“局部痤疮瘢痕治疗”或“FAST”）的安全性和有效性。
本回顾性病例系列研究在纽约州纽约市的施韦格皮肤科进行，研究对象为2011年11月至2012年5月期间接受治疗的患者。总体而言，6名患者（年龄18至48岁）接受了分次二氧化碳激光换肤术，采用所谓的“FAST”技术，仅治疗痤疮瘢痕，不治疗正常皮肤。评估基于医生和患者对治疗后1周和4周改善情况的评估。
所有6名接受分次二氧化碳激光换肤术局部痤疮瘢痕治疗技术的患者治疗后均有显著改善，治疗皮肤科医生和患者估计在治疗后4周改善程度为40%至70%。采用FAST方法后患者满意度较高。两名患者出现了暂时性炎症后色素沉着，但在单次1550纳米铒玻璃分次激光治疗后消退。
局部痤疮瘢痕治疗技术是改善萎缩性痤疮瘢痕外观的有效方法。使用该技术时可采用更高的能量和密度水平，与全脸分次二氧化碳激光换肤术相比，效果更佳。该技术愈合更快，且未发现永久性不良事件发生率增加。需要更多研究来进一步评估这项新技术。
