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鼻硬结克雷伯菌对体外纤毛活动的影响:对萎缩性鼻炎发病机制的启示

Effect of Klebsiella ozaenae on ciliary activity in vitro: implications in the pathogenesis of atrophic rhinitis.

作者信息

Ferguson J L, McCaffrey T V, Kern E B, Martin W J

机构信息

Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905.

出版信息

Otolaryngol Head Neck Surg. 1990 Mar;102(3):207-11. doi: 10.1177/019459989010200301.

DOI:10.1177/019459989010200301
PMID:2108406
Abstract

Klebsiella ozaenae is a gram-negative rod that has been isolated with relative frequency from patients with atrophic rhinitis. The relationship of this bacterium to the pathogenesis of atrophic rhinitis is not understood, and whether this bacterium is simply an opportunistic colonizer of the injured nose or the etiologic agent of the disease is unclear. This study was designed to investigate a potential role for bacterially produced cilioinhibition as a mechanism for the pathogenesis of atrophic rhinitis.

摘要

臭鼻克雷伯菌是一种革兰氏阴性杆菌,相对频繁地从萎缩性鼻炎患者中分离出来。这种细菌与萎缩性鼻炎发病机制之间的关系尚不清楚,而且这种细菌究竟只是受损鼻腔的机会性定植菌还是该疾病的病原体也不明确。本研究旨在探讨细菌产生的纤毛抑制作用作为萎缩性鼻炎发病机制的一种潜在作用。

相似文献

1
Effect of Klebsiella ozaenae on ciliary activity in vitro: implications in the pathogenesis of atrophic rhinitis.鼻硬结克雷伯菌对体外纤毛活动的影响:对萎缩性鼻炎发病机制的启示
Otolaryngol Head Neck Surg. 1990 Mar;102(3):207-11. doi: 10.1177/019459989010200301.
2
[Isolation of Klebsiella ozaenae in patients with atrophic rhinitis].
Rev Invest Salud Publica. 1973 Jul-Dec;33(3-4):143-9.
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Ciliary ultrastructure and nasal mucociliary clearance in chronic and allergic rhinitis.
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[Comparison of the mucociliary transport rate of rhinitis sicca and atrophic rhinitis].[干燥性鼻炎与萎缩性鼻炎的黏液纤毛传输速率比较]
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Ciliary disorientation: a possible variant of primary ciliary dyskinesia.睫状体定向障碍:原发性睫状运动障碍的一种可能变体。
Thorax. 1993 Jul;48(7):770-1. doi: 10.1136/thx.48.7.770.
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[Interrelations between Klebsiella ozaenae and other members of a microbial association in a pathological ozenous focus].
Zh Mikrobiol Epidemiol Immunobiol. 1988 Feb(2):17-20.
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[Chronic atrophic rhinitis and Klebsiella ozaenae infection].[慢性萎缩性鼻炎与臭鼻克雷伯菌感染]
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Porcine atrophic rhinitis: a model for studying nasal physiology and pathophysiology.猪萎缩性鼻炎:一种用于研究鼻腔生理和病理生理学的模型。
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[Atrophic rhinitis and Klebsiella ozaenae. Reflections apropos of a case].[萎缩性鼻炎与臭鼻克雷伯菌。关于一例病例的思考]
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Chin Med J (Engl). 1986 Dec;99(12):969-72.

引用本文的文献

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Ozena in Immigrants of Differing Backgrounds.不同背景移民中的臭鼻症
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Primary atrophic rhinitis: a clinical profile, microbiological and radiological study.原发性萎缩性鼻炎:一项临床特征、微生物学及放射学研究。
ISRN Otolaryngol. 2012 Nov 19;2012:404075. doi: 10.5402/2012/404075. Print 2012.
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Skull base defect in a patient with ozena undergoing dacryocystorhinostomy.一名患有臭鼻症的患者在进行泪囊鼻腔吻合术时出现颅底缺损。
Allergy Rhinol (Providence). 2011 Jan;2(1):36-9. doi: 10.2500/ar.2011.2.0007.
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BSACI guidelines for the management of allergic and non-allergic rhinitis.英国变态反应与临床免疫学会变应性和非变应性鼻炎管理指南。
Clin Exp Allergy. 2008 Jan;38(1):19-42. doi: 10.1111/j.1365-2222.2007.02888.x.
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Clinical, genetic and immunologic analysis of a family affected by ozena.
Eur Arch Otorhinolaryngol. 2003 Aug;260(7):390-4. doi: 10.1007/s00405-002-0571-x. Epub 2003 Mar 26.