[Interrelations between Klebsiella ozaenae and other members of a microbial association in a pathological ozenous focus].

The study of relationships between individual representatives of the microeubiosis at a pathological ozenous focus has shown that Gram-positive microorganisms and opportunistic enterobacteria are not antagonistic to K. ozaenae which, in their turn, do not affect the growth of opportunistic enterobacteria and Pseudomonas aeruginosa. The overwhelming majority of P. aeruginosa strains (92.9%) grown on a solid culture medium are characterized by a varying antagonistic activity with respect to K. ozaenae; this activity does not manifest if these organisms have been grown together in a liquid medium. P. aeruginosa culture fluid diluted 1:10 and 1:20 has not inhibited the multiplication of K. ozaenae. The data indicate the possibility of a prolonged coexistence of K. ozaenae with Proteus and P. aeruginosa, which is confirmed by many cases of simultaneous isolation of associations of these microbes from ozena patients. Thus the possibility appears of a combined pathogenic action of these bacteria on human body.