• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal antimicrobial therapy and hyperbaric oxygen.儿童急性淋巴细胞白血病合并肉芽肿性阿米巴脑炎经多模式抗菌治疗和高压氧治疗成功治愈。
J Clin Microbiol. 2011 Jan;49(1):446-8. doi: 10.1128/JCM.01456-10. Epub 2010 Nov 17.
2
Current research on free-living amebae causing granulomatous amebic encephalitis.关于引起肉芽肿性阿米巴脑炎的自由生活阿米巴的当前研究。
J Eukaryot Microbiol. 2001;Suppl:3S. doi: 10.1111/j.1550-7408.2001.tb00432.x.
3
Granulomatous amoebic encephalitis caused by Acanthamoeba amoebae of genotype T2 in a human immunodeficiency virus-negative patient.一名人类免疫缺陷病毒阴性患者中由T2基因型棘阿米巴原虫引起的肉芽肿性阿米巴脑炎。
J Clin Microbiol. 2008 Jan;46(1):338-40. doi: 10.1128/JCM.01177-07. Epub 2007 Nov 14.
4
Acanthamoeba infection in an interhemispheric ependymal cyst: a case report.半球间室管膜囊肿中的棘阿米巴感染：一例报告。
Surg Neurol. 2009 Aug;72(2):185-9. doi: 10.1016/j.surneu.2008.04.008. Epub 2008 Jul 9.
5
Acanthamoeba encephalitis: isolation of genotype T1 in mycobacterial liquid culture medium.棘阿米巴脑炎：在分枝杆菌液体培养基中分离出T1基因型。
J Clin Microbiol. 2015 Feb;53(2):735-9. doi: 10.1128/JCM.02887-14. Epub 2014 Dec 10.
6
Granulomatous amebic encephalitis caused by Acanthamoeba in an immuncompetent child.免疫功能正常儿童由棘阿米巴引起的肉芽肿性阿米巴脑炎。
Turk J Pediatr. 2018;60(3):340-343. doi: 10.24953/turkjped.2018.03.019.
7
Granulomatous amebic encephalitis: an under-recognized cause of infectious mortality after hematopoietic stem cell transplantation.肉芽肿性阿米巴脑炎：造血干细胞移植后未被充分认识的感染性死亡原因。
Transpl Infect Dis. 2011 Aug;13(4):366-73. doi: 10.1111/j.1399-3062.2011.00612.x. Epub 2011 Feb 21.
8
Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.在脑脊液常规细胞学检查期间对棘阿米巴感染进行早期诊断。
J Clin Microbiol. 2006 May;44(5):1903-4. doi: 10.1128/JCM.44.5.1903-1904.2006.
9
Acanthamoeba encephalitis in patient with systemic lupus, India.印度系统性红斑狼疮患者的棘阿米巴脑炎
Emerg Infect Dis. 2006 Jun;12(6):984-6. doi: 10.3201/eid1206.060087.
10
[Amebic meningoencephalitis].[阿米巴性脑膜脑炎]
Brain Nerve. 2009 Feb;61(2):115-21.

引用本文的文献

1
Hyperbaric oxygen therapy for brain abscesses: A useful adjuvant treatment for a faster recovery.高压氧疗法治疗脑脓肿：一种有助于更快康复的辅助治疗方法。
Neurosurg Rev. 2025 Jul 30;48(1):583. doi: 10.1007/s10143-025-03721-9.
2
Disseminated infection in a patient with AIDS: a case report and literature review.艾滋病患者的播散性感染：一例病例报告及文献综述
Front Med (Lausanne). 2024 Jun 17;11:1377302. doi: 10.3389/fmed.2024.1377302. eCollection 2024.
3
Granulomatous Amebic Encephalitis Presenting Like a Tumor-Chasing a Diagnostic Conundrum.表现为肿瘤样的肉芽肿性阿米巴脑炎——追寻诊断难题
Ann Indian Acad Neurol. 2021 Nov-Dec;24(6):968-970. doi: 10.4103/aian.AIAN_994_20. Epub 2021 Oct 7.
4
Case Report: First Successful Treatment of Acanthamoeba Brain Abscess with Combination Surgical Excision and Miltefosine-Led Antimicrobial Therapy.病例报告：联合手术切除和米替福新主导的抗菌治疗首次成功治愈棘阿米巴脑脓肿。
Am J Trop Med Hyg. 2022 Jan 17;106(3):861-866. doi: 10.4269/ajtmh.21-0166.
5
Opportunistic free-living amoebal pathogens.机会致病性自由生活阿米巴病原体。
Pathog Glob Health. 2022 Mar;116(2):70-84. doi: 10.1080/20477724.2021.1985892. Epub 2021 Oct 2.
6
Acanthamoeba castellanii encephalitis in a patient with AIDS: a case report and literature review.艾滋病患者中棘阿米巴脑炎：病例报告及文献复习。
Lancet Infect Dis. 2022 Feb;22(2):e59-e65. doi: 10.1016/S1473-3099(20)30933-6. Epub 2021 Aug 27.
7
Immunopathogenicity of spp. in the Brain and Lungs.脑和肺中 spp. 的免疫发病机制。
Int J Mol Sci. 2021 Jan 27;22(3):1261. doi: 10.3390/ijms22031261.
8
In vitro activity of Camellia sinensis (green tea) against trophozoites and cysts of Acanthamoeba castellanii.绿茶（Camellia sinensis）提取物抗福氏耐格里阿米巴滋养体和包囊的体外实验研究。
Int J Parasitol Drugs Drug Resist. 2020 Aug;13:59-72. doi: 10.1016/j.ijpddr.2020.05.001. Epub 2020 Jun 2.
9
Amoebic encephalitis: case report and literature review of neuroimaging findings.阿米巴性脑炎：病例报告及神经影像学检查结果的文献综述
BJR Case Rep. 2016 Jul 28;2(3):20150499. doi: 10.1259/bjrcr.20150499. eCollection 2016.
10
Postoperative infection caused by Acinetobacter baumannii misdiagnosed as a free-living amoeba species in a humeral head hemiarthroplasty patient: a case report.肱骨头半髋关节置换术后患者因鲍曼不动杆菌感染误诊为自由生活阿米巴病：1 例报告。
Infect Dis Poverty. 2018 Mar 31;7(1):33. doi: 10.1186/s40249-018-0408-5.

本文引用的文献

1
Management of brain abscesses in children treated for acute lymphoblastic leukemia.急性淋巴细胞白血病患儿脑脓肿的管理
Pediatr Blood Cancer. 2009 Mar;52(3):408-11. doi: 10.1002/pbc.21814.
2
Acanthamoeba infection in a patient with chronic graft-versus-host disease occurring during treatment with voriconazole.一名患有慢性移植物抗宿主病的患者在伏立康唑治疗期间发生棘阿米巴感染。
Transpl Infect Dis. 2008 Dec;10(6):437-41. doi: 10.1111/j.1399-3062.2008.00335.x. Epub 2008 Aug 13.
3
Cure of Acanthamoeba cerebral abscess in a liver transplant patient.肝移植患者棘阿米巴脑脓肿的治愈
Liver Transpl. 2008 Mar;14(3):308-12. doi: 10.1002/lt.21409.
4
Successful treatment of acanthamoeba meningoencephalitis during induction therapy of childhood acute lymphoblastic leukemia.儿童急性淋巴细胞白血病诱导治疗期间棘阿米巴脑膜脑炎的成功治疗。
Pediatr Blood Cancer. 2008 Jun;50(6):1292-3. doi: 10.1002/pbc.21477.
5
Fatal granulomatous Acanthamoeba encephalitis mimicking a stroke, diagnosed by correlation of results of sequential magnetic resonance imaging, biopsy, in vitro culture, immunofluorescence analysis, and molecular analysis.通过连续磁共振成像、活检、体外培养、免疫荧光分析和分子分析结果的相互关联诊断出的酷似中风的致命性肉芽肿性棘阿米巴脑炎。
J Clin Microbiol. 2006 Nov;44(11):4265-9. doi: 10.1128/JCM.00649-06. Epub 2006 Sep 20.
6
Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.在脑脊液常规细胞学检查期间对棘阿米巴感染进行早期诊断。
J Clin Microbiol. 2006 May;44(5):1903-4. doi: 10.1128/JCM.44.5.1903-1904.2006.
7
Hyperbaric oxygen therapy for the treatment of brain abscess in children.高压氧疗法治疗儿童脑脓肿
Childs Nerv Syst. 2006 Jan;22(1):38-42. doi: 10.1007/s00381-005-1147-z. Epub 2005 May 5.
8
Opportunistic amoebae: challenges in prophylaxis and treatment.机会性变形虫：预防与治疗中的挑战
Drug Resist Updat. 2004 Feb;7(1):41-51. doi: 10.1016/j.drup.2004.01.002.
9
Acanthamoeba castellani encephalitis following partially mismatched related donor peripheral stem cell transplantation.部分匹配的相关供体外周干细胞移植后发生卡氏棘阿米巴脑炎。
Transpl Infect Dis. 2003 Dec;5(4):191-4. doi: 10.1111/j.1399-3062.2003.00029.x.
10
Acanthamoeba spp. as agents of disease in humans.棘阿米巴属作为人类疾病的病原体。
Clin Microbiol Rev. 2003 Apr;16(2):273-307. doi: 10.1128/CMR.16.2.273-307.2003.

儿童急性淋巴细胞白血病合并肉芽肿性阿米巴脑炎经多模式抗菌治疗和高压氧治疗成功治愈。

Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal antimicrobial therapy and hyperbaric oxygen.

机构信息

Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 30, 8036 Graz, Austria.

出版信息

J Clin Microbiol. 2011 Jan;49(1):446-8. doi: 10.1128/JCM.01456-10. Epub 2010 Nov 17.

DOI:10.1128/JCM.01456-10
PMID:21084511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3020488/
Abstract

Acanthamoeba is the causative agent of granulomatous amebic encephalitis, a rare and usually fatal disease. We report a child with acute lymphoblastic leukemia who developed brain abscesses caused by Acanthamoeba during induction therapy. Multimodal antimicrobial chemotherapy and hyperbaric oxygen therapy resulted in complete resolution of symptoms and of pathology as seen by magnetic resonance imaging.

摘要

棘阿米巴是肉芽肿性阿米巴脑炎的病原体，这是一种罕见且通常致命的疾病。我们报告了一例在诱导治疗期间发生棘阿米巴引起的脑脓肿的急性淋巴细胞白血病患儿。多模式抗菌化疗和高压氧治疗导致症状和磁共振成像所见的病理学完全缓解。