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前交叉韧带重建后至少 6 年的运动功能和活动的预后和预测因素:一项人群队列研究。

The prognosis and predictors of sports function and activity at minimum 6 years after anterior cruciate ligament reconstruction: a population cohort study.

机构信息

Vanderbilt Sports Medicine, 4200 Medical Center East, South Tower, 1215 21st Ave South, Nashville, TN 37232-8774, USA.

出版信息

Am J Sports Med. 2011 Feb;39(2):348-59. doi: 10.1177/0363546510383481. Epub 2010 Nov 17.

Abstract

BACKGROUND

The predictors of anterior cruciate ligament reconstruction (ACLR) outcome at 6 years as measured by validated patient-based outcome instruments are unknown.

HYPOTHESIS

Certain variables evaluated at the time of ACLR will predict return to sports function (as measured by the International Knee Documentation Committee [IKDC] questionnaire and the Knee injury and Osteoarthritis Outcome Score [KOOS] Sports and Recreation subscale), knee-related quality of life (KOOS Knee Related Quality of Life subscale), and activity level (Marx Activity Scale). Potential predictor variables include demographic factors, surgical technique and graft choice for ACLR, and intra-articular injuries and treatment.

STUDY DESIGN

Cohort study; Level of evidence, 2.

METHODS

All patients with unilateral ACLRs from 2002 currently enrolled in the MOON (Multicenter Orthopaedic Outcomes Network) cohort were evaluated. Patients completed the validated outcome instruments preoperatively. Physicians documented intra-articular pathologic abnormalities, treatment, and surgical techniques used at the time of surgery. At 2 and 6 years postoperatively, patients completed the same validated outcome instruments.

RESULTS

Follow-up was obtained at 2 years (88%) and at 6 years (84%). The cohort was 57% male with a median age of 23 years at enrollment. The ability to perform sports function was maintained at 6 years, but the Marx activity level continued to decline from baseline. Revision ACLR and use of allograft predicted worse outcomes on the IKDC and both KOOS subscales. Lateral meniscus treatment, smoking status, and body mass index at baseline were each predictors on 2 of 3 scales. The predictors of lower activity level were revision ACLR and female sex.

CONCLUSION

Six years after ACLR, patients could perform sports-related functions and maintain a high knee-related quality of life similar to their 2-year level, although their physical activity level (Marx) dropped over time. Choosing autograft rather than allograft, not smoking, and having normal body mass index are advised to improve long-term outcomes.

摘要

背景

使用经过验证的基于患者的结果评估工具测量,6 年后前交叉韧带重建(ACLR)的结果的预测因素尚不清楚。

假说

在 ACLR 时评估的某些变量将预测重返运动功能(通过国际膝关节文献委员会 [IKDC] 问卷和膝关节损伤和骨关节炎结果评分 [KOOS] 运动和娱乐子量表测量)、膝关节相关生活质量(KOOS 膝关节相关生活质量子量表)和活动水平(马克思活动量表)。潜在的预测因素包括人口统计学因素、ACLR 的手术技术和移植物选择,以及关节内损伤和治疗。

研究设计

队列研究;证据水平,2 级。

方法

评估了目前在 MOON(多中心矫形结果网络)队列中登记的所有 2002 年单侧 ACLR 的患者。患者在术前完成了经过验证的结果评估工具。医生记录了手术时关节内病理异常、治疗和手术技术。术后 2 年和 6 年,患者完成了相同的经过验证的结果评估工具。

结果

在 2 年(88%)和 6 年(84%)时获得了随访。队列中 57%为男性,入组时的中位年龄为 23 岁。6 年后仍能保持运动功能,但马克思活动水平从基线开始继续下降。翻修 ACLR 和使用同种异体移植物预测 IKDC 和 KOOS 两个子量表的结果更差。外侧半月板治疗、吸烟状况和基线时的体重指数在 3 个量表中的 2 个上都是预测因素。较低活动水平的预测因素是翻修 ACLR 和女性。

结论

ACL 重建后 6 年,患者可以进行与运动相关的功能,并且保持类似于 2 年的高水平膝关节相关生活质量,尽管他们的体力活动水平(马克思)随着时间的推移而下降。建议选择自体移植物而不是同种异体移植物、不吸烟和保持正常体重指数,以改善长期结果。

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