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[Therapeutic options for haemangiomas of infancy].

作者信息

Krause H, Haß H-J, Kroker S, Meyer F, Halloul Z, Wagemann W

机构信息

Universitätsklinikum Magdeburg, Arbeitsbereich Kinderchirurgie, Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Magdeburg, Deutschland.

出版信息

Zentralbl Chir. 2012 Oct;137(5):446-52. doi: 10.1055/s-0030-1247323. Epub 2010 Nov 17.

DOI:10.1055/s-0030-1247323
PMID:21086249
Abstract

The necessity of haemangioma treatment in infants has been controversially discussed for years. One reason is the favoured clinical observation of a potential spontaneous involution without any therapeutic approach or medical treatment, thus avoiding their specific risks. On the other hand, there are several reports on serious cases with -rapidly growing haemangiomas including severe consequences. There are potential complications such as loss of visus in cases of periorbital manifestation. A basic problem is the lack of a unique systematic classification, on the basis of which -diagnostic measures, therapeutic indications and modes could be compared. Such a classification would be much more competent including a sufficient comparison of treatment results. The basic aim in management is to achieve control of the haemangioma growth and induction of its sub-sequent involution back to only a cosmetic detraction. Each threatening functional loss can be classified as an urgent indication for treatment. There is a need to consider the treatment options and their values; in particular, cryotherapy or laser therapy in localised manifestations are mostly -favoured because of the convincing evidence from available data. In the case of a more disseminated haemangioma manifestation, the initiation of propranol medication is possible, a novel drug for this indication. However, there are no follow-up data on the mid-term or long-term outcome available at this time. Further studies on the subject are therefore required.

摘要

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