Derbyshire Children's Hospital, Uttoxeter Road, Derby DE22 3NE, UK.
Arch Dis Child. 2011 Sep;96(9):890-3. doi: 10.1136/adc.2010.208884. Epub 2011 May 28.
Infantile haemangiomas are the most common benign tumour of infancy. However the majority are self-resolving and only a small minority of cases require treatment, with various different medications being used in the past. Over the last few years, propranolol, a non-selective β-blocker, has become a popular and successful treatment for infantile haemangiomas. However, further research on its safety is needed if it is going to be used more frequently. This article summarises the current literature on propranolol for haemangioma treatment with emphasis on its toxicity and adverse event profile.
婴儿血管瘤是最常见的婴幼儿良性肿瘤。然而，大多数血管瘤会自行消退，只有少数病例需要治疗，过去曾使用过各种不同的药物。在过去的几年中，普萘洛尔作为一种非选择性β受体阻滞剂，已成为治疗婴儿血管瘤的一种流行且有效的方法。然而，如果要更频繁地使用它，还需要进一步研究其安全性。本文总结了普萘洛尔治疗血管瘤的最新文献，重点介绍了其毒性和不良事件概况。
