Norredam Marie, Jensen Mette, Ekstrøm Morten
Danish Research Centre on Migration, Ethnicity and Health, Department of Public Health, University of Copenhagen & Psychiatric Trauma Clinic for Refugees, Gentofte Hospital, Copenhagen, Denmark.
Nord J Psychiatry. 2011 Sep;65(4):283-8. doi: 10.3109/08039488.2010.533385. Epub 2010 Nov 18.
In our clinical work, we treat refugees who have been exposed to trauma and who subsequently develop psychotic symptoms. However, the literature does not address the relationship between refugees with depression, post-traumatic stress disorder (PTSD) and psychotic symptoms. Therefore the aim of this study is firstly to present a series of cases showing how psychotic symptoms may present in refugees diagnosed with PTSD, and secondly to discuss the underlying explanations of the involved psychopathology.
The study is based on a presentation of a series of cases. All six cases were selected as they fulfilled the following criteria for inclusion: 1) had a refugee background, 2) fulfilled the PTSD (F43.1) diagnosis upon treatment start and 3) revealed psychotic symptoms during treatment. All six were outpatients at the Psychiatric Trauma Clinic for Refugees at Psychiatric Centre Gentofte in Copenhagen during 2009.
Our cases were all characterized by having severe symptoms of depression and PTSD. Before treatment start they had a score on the Harvard Trauma Questionnaire between 2.9 and 3.8 (cut-off: 2.5), and a score on the Hopkins Symptom Checklist-25 between 2.8 and 3.6 (cut-off: 1.8). Additionally, all cases suffered from varying degrees of positive psychotic symptoms, including auditory hallucinations, olfactory and visual hallucinations, as well as persecutory delusions and delusions of reference.
In conclusion, research is needed into the prevalence of psychotic symptoms among refugees with depression and PTSD, including the qualitative dimensions of the symptoms in order to optimize diagnosis and treatment among this group of psychiatric patients.
在我们的临床工作中,我们治疗曾遭受创伤并随后出现精神病性症状的难民。然而,文献中并未涉及患有抑郁症、创伤后应激障碍(PTSD)的难民与精神病性症状之间的关系。因此,本研究的目的一是呈现一系列病例,展示精神病性症状在被诊断为PTSD的难民中是如何表现的;二是讨论所涉及精神病理学的潜在解释。
本研究基于一系列病例的呈现。所有六个病例均因符合以下纳入标准而被选中:1)有难民背景;2)在治疗开始时符合PTSD(F43.1)诊断;3)在治疗期间出现精神病性症状。所有六个病例在2009年期间均为哥本哈根根措夫特精神病中心难民精神创伤诊所的门诊患者。
我们的病例均以严重的抑郁和PTSD症状为特征。在治疗开始前,他们在哈佛创伤问卷上的得分在2.9至3.8之间(临界值:2.5),在霍普金斯症状清单 - 25上的得分在2.8至3.6之间(临界值:1.8)。此外,所有病例都患有不同程度的阳性精神病性症状,包括幻听、幻嗅和幻视,以及被害妄想和关系妄想。
总之,需要对患有抑郁症和PTSD的难民中精神病性症状的患病率进行研究,包括症状的质性维度,以便优化这组精神科患者的诊断和治疗。