Department of General & Bariatric Surgery, Southmead Hospital, Bristol, UK.
Obes Surg. 2011 Feb;21(2):161-6. doi: 10.1007/s11695-010-0307-8.
The purpose of this study was to determine whether laparoscopic adjustable gastric banding has a role in the treatment of idiopathic intracranial hypertension. This pilot study was undertaken in a single, tertiary referral centre. Data on all patients with idiopathic intracranial hypertension that have undergone laparoscopic adjustable gastric banding in our unit were collected from our prospectively maintained bariatric database. Additional information was obtained via telephone questionnaires and review of medical records. Four female patient with a mean age of 32 years (range 29-39 years) and mean pre-operative body mass index of 46.1 kg/m(2) (range 38.2-54.0 kg/m(2)) underwent laparoscopic adjustable gastric banding between June 2006 and July 2009. At a mean follow-up of 19.8 months all four patients reported either total resolution of headache or significant improvement in headache, with a mean improvement in pain score of 76.3/100 (range 55-95) on a analogue pain score. Mean excess weight loss at follow-up was 64.1% (range 50.1-88.2%). There were no complications or mortality in this cohort. This study suggests that laparoscopic adjustable gastric banding represents an effective and safe treatment for idiopathic intracranial hypertension associated with morbid obesity. We have shown good results both in terms of symptom resolution and weight loss, whilst avoiding alimentary tract diversion procedures in these young female patients. A randomized, controlled trial can be justified on the basis of this initial pilot study.
本研究旨在探讨腹腔镜可调节胃束带术在治疗特发性颅内高压中的作用。该前瞻性研究在一家单中心三级转诊中心进行。从我们前瞻性维持的减肥数据库中收集了我院所有接受腹腔镜可调节胃束带术治疗的特发性颅内高压患者的数据。通过电话问卷调查和病历回顾获得了额外的信息。4 名女性患者,平均年龄 32 岁(范围 29-39 岁),平均术前体重指数为 46.1kg/m²(范围 38.2-54.0kg/m²),于 2006 年 6 月至 2009 年 7 月期间接受了腹腔镜可调节胃束带术。平均随访 19.8 个月后,所有 4 例患者均报告头痛完全缓解或显著改善,模拟疼痛评分平均改善 76.3/100(范围 55-95)。随访时平均超重减轻 64.1%(范围 50.1-88.2%)。该队列中无并发症或死亡。本研究表明,腹腔镜可调节胃束带术是治疗与病态肥胖相关的特发性颅内高压的有效、安全的治疗方法。我们在症状缓解和体重减轻方面均取得了良好的效果,同时避免了这些年轻女性患者进行消化道转流手术。基于这项初步的试点研究,可以进行随机、对照试验。