[甲状旁腺激素低钙血症活性期大鼠组织中环磷酸腺苷的研究]
[Study of cyclic AMP in rat tissue during the phase of hypocalcemic activity of parathyroid hormone].
作者信息
Marnay-Gulat C, Youyou A, Labitte A, Raoul Y
出版信息
C R Seances Soc Biol Fil. 1978;172(2):225-30.
PMID:210903
Abstract
As soon as two minutes after PTH i.v. injection the blood and kidney AMPc level is maximally increased but the lowering blood calcium effect remained till to ten minutes. At this time the calvaria AMPc level reached its maximum just at the onset of hypercalcemic effect of PTH. Thus AMPc increase in tissues is consistent with the two opposite effects of PTH.
摘要
静脉注射甲状旁腺激素（PTH）后两分钟内，血液和肾脏中的环磷酸腺苷（AMPc）水平即达到最大程度升高，但血钙降低效应一直持续到十分钟。此时，顶骨的AMPc水平恰好在PTH的高钙血症效应开始时达到最大值。因此，组织中AMPc的增加与PTH的两种相反作用是一致的。
相似文献
1
[Study of cyclic AMP in rat tissue during the phase of hypocalcemic activity of parathyroid hormone].[甲状旁腺激素低钙血症活性期大鼠组织中环磷酸腺苷的研究]
C R Seances Soc Biol Fil. 1978;172(2):225-30.
2
Inhibition of parathyroid hormone secretion and parathyroid hormone-independent diminution of tubular calcium reabsorption by WR-2721, a unique hypocalcemic agent.独特的降钙血药WR-2721对甲状旁腺激素分泌的抑制作用以及对肾小管钙重吸收的非甲状旁腺激素依赖性减少作用。
J Clin Invest. 1985 Nov;76(5):1851-6. doi: 10.1172/JCI112178.
3
The hypercalcemic effect of parathyroid hormone and skeletal cyclic AMP.
Endocrinology. 1975 Mar;96(3):725-31. doi: 10.1210/endo-96-3-725.
4
[Norepinephrine interference in adrenal hormone balance related to blood calcium effects of PTH (author's transl)].去甲肾上腺素对与甲状旁腺激素血钙效应相关的肾上腺激素平衡的干扰（作者译）
J Physiol (Paris). 1977 Oct;73(5):653-62.
5
Regulation of the receptor-mediated cyclic AMP response of kidney to parathyroid hormone in the vitamin D-deficient rat.维生素D缺乏大鼠肾脏中甲状旁腺激素受体介导的环磷酸腺苷反应的调节
J Supramol Struct. 1978;9(2):179-88. doi: 10.1002/jss.400090204.
6
Inhibition of carbonic anhydrase by parathyroid hormone and cyclic AMP in rat renal cortex in vitro.甲状旁腺激素和环磷酸腺苷对大鼠肾皮质碳酸酐酶的体外抑制作用。
J Clin Invest. 1975 Jan;55(1):149-56. doi: 10.1172/JCI107905.
7
8
Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function.原发性低镁血症中低钙血症的发病机制：终末器官对甲状旁腺激素反应正常，甲状旁腺功能受损。
J Clin Invest. 1973 Jan;52(1):153-60. doi: 10.1172/JCI107159.
9
Effect of chronic ethanol consumption on the response of parathyroid hormone to hypocalcemia in the pregnant rat.长期乙醇摄入对妊娠大鼠甲状旁腺激素对低钙血症反应的影响。
Alcohol Clin Exp Res. 2007 Jan;31(1):104-12. doi: 10.1111/j.1530-0277.2006.00268.x.
10
Parathyroid hormone 7-84 induces hypocalcemia and inhibits the parathyroid hormone 1-84 secretory response to hypocalcemia in rats with intact parathyroid glands.甲状旁腺激素7 - 84可诱发低钙血症，并抑制甲状旁腺完整的大鼠对低钙血症产生的甲状旁腺激素1 - 84分泌反应。
J Am Soc Nephrol. 2006 Jul;17(7):1923-30. doi: 10.1681/ASN.2005101136. Epub 2006 May 17.
Zotero 插件