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[甲状旁腺激素低钙血症活性期大鼠组织中环磷酸腺苷的研究]

[Study of cyclic AMP in rat tissue during the phase of hypocalcemic activity of parathyroid hormone].

作者信息

Marnay-Gulat C, Youyou A, Labitte A, Raoul Y

出版信息

C R Seances Soc Biol Fil. 1978;172(2):225-30.

PMID:210903
Abstract

As soon as two minutes after PTH i.v. injection the blood and kidney AMPc level is maximally increased but the lowering blood calcium effect remained till to ten minutes. At this time the calvaria AMPc level reached its maximum just at the onset of hypercalcemic effect of PTH. Thus AMPc increase in tissues is consistent with the two opposite effects of PTH.

摘要

静脉注射甲状旁腺激素(PTH)后两分钟内,血液和肾脏中的环磷酸腺苷(AMPc)水平即达到最大程度升高,但血钙降低效应一直持续到十分钟。此时,顶骨的AMPc水平恰好在PTH的高钙血症效应开始时达到最大值。因此,组织中AMPc的增加与PTH的两种相反作用是一致的。

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1
[Study of cyclic AMP in rat tissue during the phase of hypocalcemic activity of parathyroid hormone].[甲状旁腺激素低钙血症活性期大鼠组织中环磷酸腺苷的研究]
C R Seances Soc Biol Fil. 1978;172(2):225-30.
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