QOPNA/Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
ACS Nano. 2010 Dec 28;4(12):7133-40. doi: 10.1021/nn1026092. Epub 2010 Nov 19.
Cationic nanomagnet-porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (-) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet-porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection.
阳离子纳米磁体-卟啉杂化物被合成，并研究了它们对革兰氏阴性大肠杆菌、革兰氏阳性粪肠球菌和 T4 样噬菌体的光动力治疗能力。讨论了这些新材料的合成、结构表征、光物理性质和抗菌活性。结果表明，这些新型多电荷纳米磁体-卟啉杂化物在水中非常稳定，并且在细菌和噬菌体的光灭活方面非常有效。它们显著的抗菌活性，以及它们易于通过施加磁场来回收的特点，使这些材料成为水或废水消毒的新型光敏剂。
