State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, PR China.
Langmuir. 2011 Feb 15;27(4):1398-402. doi: 10.1021/la103917x. Epub 2010 Nov 24.
Dynamic self-assembly of nonvolatile solutes via controlled solvent evaporation has been exploited as a simple route to create a variety of hierarchically assembled structures. In this work, two glass slides were used to form a confined space in which a solution of a rodlike nanoparticle, tobacco mosaic virus (TMV), was evaporated to create large-scale stripe patterns. The height and width of the stripes are dependent on the TMV concentration. The large-scale-patterned surfaces can be applied to control surface hydrophobicity and direct the growth of bone marrow stromal cells. We systematically studied the effects of stripe width and height on surface hydrophobicity using optical microscopy, atomic force microscopy, and contact angle measurements. This technique offers a facile approach to form 2D patterns on a large surface from a wide range of proteins as well as other biomacromolecules.
通过控制溶剂蒸发来实现非挥发性溶质的动态自组装，已经被开发为一种简单的方法来创建各种层次组装结构。在这项工作中，使用两个玻璃片在其中形成一个受限空间，其中蒸发了棒状纳米颗粒烟草花叶病毒（TMV）的溶液，以产生大规模的条纹图案。条纹的高度和宽度取决于 TMV 的浓度。这种大规模图案化的表面可用于控制表面疏水性并指导骨髓基质细胞的生长。我们使用光学显微镜、原子力显微镜和接触角测量系统地研究了条纹宽度和高度对表面疏水性的影响。这种技术为从广泛的蛋白质以及其他生物大分子在大表面上形成 2D 图案提供了一种简单的方法。
