Institute of Cancer Epidemiology, Copenhagen, Denmark.
Acta Oncol. 2011 Feb;50(2):265-73. doi: 10.3109/0284186X.2010.529823. Epub 2010 Nov 22.
Few studies have been conducted on the socioeconomic position of women undergoing breast reconstruction, and none have been conducted in the Danish population. We investigated the association between educational level and breast reconstruction in a nationwide cohort of Danish women with breast cancer.
From nationwide registers, 13 379 women aged 30-80 years who had been treated by mastectomy for breast cancer in Denmark in 1999-2006 were identified and followed up through November 2009. Multivariate logistic regression models were used to investigate the simultaneous influence of educational level on the likelihood of having immediate or delayed (up to three years after mastectomy) breast reconstruction, with adjustment for age, breast cancer characteristics, comorbidity, socioeconomic variables and availability of plastic surgery services at each woman's affiliated hospital.
The odds ratios (ORs) for both immediate and delayed breast reconstruction increased significantly with level of education. Being affiliated to a hospital with a plastic surgery department increased the likelihood of both immediate (adjusted OR, 4.02; 95% confidence interval [CI], 2.81-5.75) and delayed breast reconstruction (adjusted OR, 1.41; 95% CI, 1.26-1.66). There was no association between education and breast reconstruction among 30-44 year old women, regardless of type of breast reconstruction; however, medium or higher education was significantly associated with a fourfold increase in the OR for immediate breast reconstruction in women aged 45-59 years and a more than twofold increase in the OR for delayed breast reconstruction in women aged 60-80 years compared to women with short education.
Increasing education was associated with increasing odds for having immediate or delayed breast reconstruction, but only in the older age groups. The offer of breast reconstruction appears to be unequally distributed in Denmark, and living in an area where the hospital has a plastic surgery department significantly increased the odds for having breast reconstruction.
关于接受乳房重建的女性的社会经济地位,仅有少数研究进行过探讨,且这些研究均未在丹麦人群中开展。我们调查了丹麦全国范围内乳腺癌女性队列中教育程度与乳房重建之间的关联。
从全国性登记处,确定了 1999 年至 2006 年期间在丹麦因乳腺癌行乳房切除术且年龄在 30-80 岁的 13379 名女性,并随访至 2009 年 11 月。使用多变量逻辑回归模型,在调整年龄、乳腺癌特征、合并症、社会经济变量以及女性所属医院的整形手术服务可及性后,调查了教育程度对即刻(乳房切除术即刻)和延迟(乳房切除术 3 年内)乳房重建可能性的同时影响。
即时和延迟乳房重建的比值比(OR)均随教育程度的增加而显著升高。与有整形科的医院有关联可增加即刻(校正 OR,4.02;95%置信区间[CI],2.81-5.75)和延迟乳房重建(校正 OR,1.41;95% CI,1.26-1.66)的可能性。在 30-44 岁女性中,无论乳房重建类型如何,教育程度与乳房重建之间均无关联;然而,与受教育程度较低的女性相比,45-59 岁女性的即时乳房重建校正 OR 增加了四倍,60-80 岁女性的延迟乳房重建校正 OR 增加了两倍以上,这与中高等教育显著相关。
教育程度的提高与即刻或延迟乳房重建的几率增加相关,但仅见于年龄较大的女性。乳房重建的提供似乎在丹麦分布不均,而在有整形科的医院就诊可显著增加乳房重建的几率。