Medicosurgical Department of Digestive Diseases, AP-HP Lariboisière Hospital and Paris 7 Denis Diderot University, Paris, France.
Int J Food Sci Nutr. 2011 Mar;62(2):164-70. doi: 10.3109/09637486.2010.527323. Epub 2010 Nov 23.
The impact of the daily consumption of 15 g chicory native inulin on fecal levels of bifidobacteria, stool parameters and quality of life of elderly constipated volunteers was investigated in a randomized, double-blind, controlled versus placebo clinical trial. The impact of supplementation on constipation was assessed with questionnaires on bowel motor function parameters, visual analogue scales on bowel symptoms and quality of life. Fecal bacteria counts were determined at the beginning and at the end of the supplementation. Inulin supplementation led to a significant increase in total fecal bacteria (P < 0.01) and bifidobacteria (P < 0.001) concentrations after 28 days of consumption. Volunteers (n = 25) in the inulin group reported increased satisfaction about digestion (P < 0.01) and reduced defecation difficulties (P < 0.001) during the supplementation. Slight gastrointestinal symptoms (flatulence) were reported but did not lead to discontinuation. Daily supplementation with 15 g inulin improves constipation and quality of life in an elderly population with constipation.
在一项随机、双盲、对照安慰剂的临床试验中,研究了每日食用 15 克菊苣天然菊粉对老年习惯性便秘志愿者粪便双歧杆菌水平、粪便参数和生活质量的影响。通过问卷调查肠道运动功能参数、肠道症状和生活质量的视觉模拟评分来评估补充剂对便秘的影响。在补充前后测定粪便细菌计数。补充菊粉 28 天后,粪便中总细菌(P < 0.01)和双歧杆菌(P < 0.001)浓度显著增加。菊粉组的志愿者(n = 25)报告在补充期间对消化的满意度增加(P < 0.01),排便困难减少(P < 0.001)。报告有轻微的胃肠道症状(胀气),但没有导致停药。每天补充 15 克菊粉可改善老年习惯性便秘人群的便秘和生活质量。