BioCirc Research Laboratory, Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
Artif Organs. 2010 Nov;34(11):1039-44. doi: 10.1111/j.1525-1594.2010.01139.x.
We are developing an intravascular axial flow blood pump to support adolescent and adult Fontan patients. To protect the blood vessel, this pump has an outer cage with radially arranged filaments and a newly designed spindle at the pump outlet. The outlet spindle is included to limit the axial movement of the rotor and to house bearings that support the rotor. This study evaluates the impact of the outlet spindle on pump performance using computational fluid dynamics (CFD) and experimental testing of a prototype configuration. We measured the pressure-flow performance of the prototype with a protective cage using a blood analog fluid. The pump with the cage filaments and spindle generated 1 to 16mmHg of pressure rise for flow rates of 1 to 4L/min at 4000 to 7000rpm. The difference between the CFD predictions and experimental results was found to be approximately 9.8%. Scalar stress levels remained below 570Pa with exposure times on the order of 1.5s. These results are acceptable and support the continued development of this cavopulmonary assist device with an outlet spindle to reinforce the protective cage filament design.
我们正在开发一种用于支持青少年和成年 Fontan 患者的血管内轴向血流血泵。为了保护血管，该血泵具有带有径向布置的细丝的外笼和在泵出口处的新设计的轴。出口轴用于限制转子的轴向运动并容纳支撑转子的轴承。本研究使用计算流体动力学 (CFD) 和原型配置的实验测试来评估出口轴对泵性能的影响。我们使用血液模拟流体测量了带有保护笼的原型的压力-流量性能。带有笼丝和轴的泵在 4000 至 7000rpm 的转速下，流量为 1 至 4L/min 时，可产生 1 至 16mmHg 的压力升高。发现 CFD 预测值与实验结果之间的差异约为 9.8%。标量应力水平保持在 570Pa 以下，暴露时间约为 1.5s。这些结果是可以接受的，并支持继续开发带有出口轴的这种心肺辅助装置，以加强保护笼丝设计。
