Korea Artificial Organ Center, Korea University, Seoul, Korea.
Artif Organs. 2010 Nov;34(11):1044-8. doi: 10.1111/j.1525-1594.2010.01143.x.
Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three-dimensional (3D) structures. It provides high-precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composition ability. Bioprinting utilizes a computer-controlled 3D printer mechanism for 3D biological structure construction. To implement minimal pattern width in a hydrogel-based bioprinting system, a study on printing characteristics was performed by varying printer control parameters. The experimental results showed that printing pattern width depends on associated printer control parameters such as printing flow rate, nozzle diameter, and nozzle velocity. The system under development showed acceptable feasibility of potential use for accurate printing pattern implementation in tissue engineering applications and is another example of novel techniques for regenerative medicine based on computer-aided biofabrication system.
生物打印是一种新兴技术，可用于构建具有复杂三维（3D）结构的组织或生物人工器官。它提供了比传统组织工程方法更高精度的空间形状形成能力，并且能够同时组合多种成分。生物打印利用计算机控制的 3D 打印机机制来构建 3D 生物结构。为了在基于水凝胶的生物打印系统中实现最小的图案宽度，通过改变打印机控制参数来研究打印特性。实验结果表明，打印图案的宽度取决于相关的打印机控制参数，如打印流速、喷嘴直径和喷嘴速度。所开发的系统显示出在组织工程应用中实现精确打印图案的潜在用途的可接受可行性，并且是基于计算机辅助生物制造系统的再生医学的新技术的另一个示例。
