通过免疫荧光技术对足月正常人类胎盘组织中碳酸酐酶I（CAI）和碳酸酐酶II（CAII）同工酶进行定位。

Localization of CAI and CAII isoenzymes in normal term human placenta by immunofluorescence techniques.

作者信息

Aliakbar S, Brown P R, Nicolaides K H

机构信息

Department of Biochemistry, Kings College London, Strand, UK.

出版信息

Placenta. 1990 Jan-Feb;11(1):35-9. doi: 10.1016/s0143-4004(05)80441-2.

DOI:10.1016/s0143-4004(05)80441-2

PMID:2109315

Abstract

The carbonic anhydrase isoenzymes, low activity CAI and high activity CAII, were localized in normal term human placenta by immunocytochemical techniques. Both CAI and CAII isoenzymes were present in the syncytial trophoblasts. Fetal erythrocytes in the placental capillaries also showed positive staining for both CAI and CAII isoenzymes. The possible physiological roles of CA in human placenta are also discussed.

摘要

通过免疫细胞化学技术，碳酸酐酶同工酶（低活性的CAI和高活性的CAII）定位在足月的正常人类胎盘中。CAI和CAII同工酶均存在于合体滋养层细胞中。胎盘毛细血管中的胎儿红细胞对CAI和CAII同工酶也呈阳性染色。本文还讨论了碳酸酐酶在人类胎盘中可能的生理作用。