颞叶癫痫的心率动力学-一项长期随访研究。
Heart rate dynamics in temporal lobe epilepsy-A long-term follow-up study.
机构信息
Department of Neurology, University of Oulu, Oulu, Finland.
出版信息
Epilepsy Res. 2011 Jan;93(1):80-3. doi: 10.1016/j.eplepsyres.2010.10.005. Epub 2010 Nov 18.
The aim of the present study was to prospectively evaluate long-term changes in interictal heart rate variability (HRV) in patients with temporal lobe epilepsy (TLE). A 24-h ECG was recorded at baseline and after a mean follow-up of 6.1 years in 18 patients with refractory TLE and 18 patients with well-controlled TLE. After the follow-up, the Poincaré components SD(1) (p=0.039) and SD(2) (p=0.001) were decreased in patients with refractory TLE compared to baseline, whereas in patients with well-controlled TLE no changes (p>0.05) in HR variability were observed. The reduction in HRV seems to be progressive in patients with chronic refractory TLE with recurrent seizures.
本研究旨在前瞻性评估颞叶癫痫（TLE）患者发作间期心率变异性（HRV）的长期变化。18 例耐药性 TLE 患者和 18 例病情控制良好的 TLE 患者在基线时和平均 6.1 年的随访后记录了 24 小时心电图。随访后，与基线相比，耐药性 TLE 患者的 Poincaré 成分 SD(1)（p=0.039）和 SD(2)（p=0.001）降低，而病情控制良好的 TLE 患者 HR 变异性无变化（p＞0.05）。在有反复发作的慢性耐药性 TLE 患者中，HRV 的降低似乎是渐进的。
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