肉毒毒素在面部年轻化中的应用：最新进展。

Botulinum toxin in facial rejuvenation: an update.

机构信息

Department of Ophthalmology and Visual Sciences, University of British Columbia, 943 West Broadway, Suite 740, Vancouver, BC, Canada V5Z 4E1.

出版信息

Obstet Gynecol Clin North Am. 2010 Dec;37(4):571-82, ix. doi: 10.1016/j.ogc.2010.10.002.

DOI:10.1016/j.ogc.2010.10.002

PMID:21093750

Abstract

Since its initial approval by the US Food and Drug Administration (FDA) 20 years ago for the treatment of strabismus, hemifacial spasm, and blepharospasm in adults, botulinum toxin (BTX) has become one of the most frequently requested products in cosmetic rejuvenation around the world. After years of clinical success and consistent safety in the upper face, the use of BTX has expanded and evolved to include increasingly complicated indications. In the hands of adept injectors, the focus has shifted from the treatment of individual dynamic rhytides to shaping, contouring, and sculpting, alone or in combination with other cosmetic procedures, to enhance the aesthetic appearance of the face. Although recent reports have questioned the safety of BTX, 25 years of therapeutic and over 20 years of cosmetic use has demonstrated an impressive record of safety and efficacy when used appropriately by experienced injectors.

摘要

20 年前，肉毒毒素（BTX）获得美国食品和药物管理局（FDA）批准，开始用于治疗成人斜视、面肌痉挛和眼睑痉挛，此后便成为全球美容领域应用最广泛的产品之一。经过多年的临床应用，其在上半脸的安全性和有效性得到了一致认可，应用范围也不断扩大，逐渐涵盖了更加复杂的适应证。在经验丰富的注射医生手中，BTX 的应用焦点已从治疗单一动态皱纹，转变为通过单独或联合其他美容治疗，对面部进行塑形、轮廓重塑和雕塑，以改善面部的美学外观。尽管最近有报道质疑 BTX 的安全性，但 25 年的治疗应用和 20 多年的美容应用记录表明，经验丰富的注射医生合理应用 BTX 可确保其具有良好的安全性和有效性。