Nordmeyer J P, Shafeh T A, Heckmann C
Medizinische Klinik, Allgemeines Krankenhaus für die Stadt Hagen, FRG.
Acta Endocrinol (Copenh). 1990 Mar;122(3):391-5. doi: 10.1530/acta.0.1220391.
Thyroid sonography was used to assess 2322 patients attending our clinic over a 3-year period. Sonography, in combination with clinical and laboratory findings, enabled us to detect autoimmune thyroiditis in 123 patients, 67 of whom could be classified as euthyroid, 17 as latent hypothyroid, and 39 as overtly hypothyroid. Consequently without the use of sonography (or thyroid antibody measurements) it would not have been possible to make a diagnosis in over half of our patients with autoimmune thyroiditis. Sonography was also of considerable value in establishing the absence of autoimmune thyroiditis as out of the 2322 patients we examined, autoimmune thyroiditis could be excluded on the basis of sonography alone (absence of diffuse hypoechoicity) in 1962 (84%). Thyroid volume ranged from less than 5 to 112 ml with the majority of patients having a volume of 21-30 ml and the overtly hypothyroid group showing a shift to smaller volumes. The data suggested that thyroid volume changes over the range of the disease from euthyroid to overtly hypothyroid.
在3年时间里，我们使用甲状腺超声对到我们诊所就诊的2322例患者进行了评估。超声检查结合临床和实验室检查结果，使我们能够在123例患者中检测出自身免疫性甲状腺炎，其中67例可归类为甲状腺功能正常，17例为潜在甲状腺功能减退，39例为显性甲状腺功能减退。因此，如果不使用超声检查（或甲状腺抗体检测），我们超过一半的自身免疫性甲状腺炎患者将无法做出诊断。超声检查在确定无自身免疫性甲状腺炎方面也具有重要价值，因为在我们检查的2322例患者中，仅根据超声检查（无弥漫性低回声）就可以排除1962例（84%）的自身免疫性甲状腺炎。甲状腺体积范围从小于5 ml到112 ml，大多数患者的体积为21 - 30 ml，显性甲状腺功能减退组的体积向较小值偏移。数据表明，在从甲状腺功能正常到显性甲状腺功能减退的疾病范围内，甲状腺体积会发生变化。
