LTi 细胞，免疫变色龙。
The LTi cell, an immunologic chameleon.
机构信息
NIH/NIAID, Bethesda, MD 20892, USA.
出版信息
Immunity. 2010 Nov 24;33(5):650-2. doi: 10.1016/j.immuni.2010.11.016.
Abstract
Lymphoid tissue inducer (LTi) cells are key components of the machinery required for the construction of the lymphoid structures underlying immune responses. In this issue of Immunity, Vonarbourg et. al. (2010) describe how these cells assume several different guises, each associated with different LTi functions.
摘要
淋巴组织诱导（LTi）细胞是构建免疫反应所必需的淋巴组织结构的关键组成部分。在本期《免疫》杂志中，Vonarbourg 等人（2010）描述了这些细胞如何呈现出几种不同的形态，每种形态都与不同的 LTi 功能相关。
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本文引用的文献
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Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.克罗恩病患者肠道黏膜中 NKp44(+)NKp46(-)和 NKp44(-)NKp46(+)自然杀伤细胞的失衡。
Gastroenterology. 2010 Sep;139(3):882-92, 892.e1-3. doi: 10.1053/j.gastro.2010.05.040. Epub 2010 Jun 1.
3
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.先天淋巴细胞驱动白细胞介素-23 依赖性固有肠道病理学。
Nature. 2010 Apr 29;464(7293):1371-5. doi: 10.1038/nature08949.
4
Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity.黏膜免疫中产生白细胞介素-22的自然杀伤细胞和类淋巴组织诱导细胞
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