Department of Cardiac Surgery, New Brunswick Heart Center, Saint John, New Brunswick, Canada.
Am Heart J. 2010 Nov;160(5):958-65. doi: 10.1016/j.ahj.2010.06.052.
Percutaneous coronary intervention (PCI) is increasingly being offered to patients with coronary artery disease. The purpose of this study was to determine the impact of this change in coronary revascularization strategy on PCI and coronary artery bypass grafting (CABG) utilization across Canada.
All cases of PCI and isolated CABG between years 1994 and 2005 were identified through the Canadian Institute for Health Information. Age- and sex-standardized rates of PCI and CABG per 100,000 population as well as PCI-to-CABG ratios were calculated by year and province and across age, sex, income, diabetes, and recent acute coronary syndrome subgroups. In addition, risk-adjusted rates of in-hospital mortality after PCI and CABG were reported by year.
Between 1994 and 2005, PCI rates increased from 85.6/100,000 to 186.7/100,000 (P < .001), whereas CABG rates remained stable (75.6/100,000-70.8/100,000; P = .43), resulting in an increase in PCI-to-CABG ratio (1.13-2.64; P < .001). Significant increases in PCI-to-CABG ratios were seen across all provinces (except Newfoundland and Alberta), as well as across all age, sex, income, diabetes, and recent acute coronary syndrome categories. Decline in risk-adjusted in-hospital mortality was seen after both CABG (3.9%-2.2%; P < .001) and PCI (1.6%-1.3%; P < .001) but appeared larger after CABG.
Since 1994, rates of PCI have increased significantly as compared to CABG. During the same period, greater declines in risk-adjusted rates of in-hospital mortality were seen among CABG versus PCI patients. Further study is needed to determine the appropriateness of PCI and CABG rates in terms of clinical outcomes and resource utilization.
经皮冠状动脉介入治疗(PCI)越来越多地应用于冠心病患者。本研究旨在确定这种冠状动脉血运重建策略的改变对加拿大 PCI 和冠状动脉旁路移植术(CABG)应用的影响。
通过加拿大卫生信息研究所确定了 1994 年至 2005 年期间所有 PCI 和单纯 CABG 的病例。按年和省计算了每 10 万人的 PCI 和 CABG 的年龄和性别标准化率以及 PCI 与 CABG 的比值,并按年龄、性别、收入、糖尿病和近期急性冠状动脉综合征亚组进行了计算。此外,还按年报告了 PCI 和 CABG 后住院死亡率的风险调整率。
1994 年至 2005 年间,PCI 率从 85.6/100,000 增加到 186.7/100,000(P<.001),而 CABG 率保持稳定(75.6/100,000-70.8/100,000;P=.43),PCI 与 CABG 的比值增加(1.13-2.64;P<.001)。所有省份(纽芬兰省和阿尔伯塔省除外)以及所有年龄、性别、收入、糖尿病和近期急性冠状动脉综合征类别均观察到 PCI 与 CABG 比值的显著增加。CABG(3.9%-2.2%;P<.001)和 PCI(1.6%-1.3%;P<.001)后风险调整住院死亡率均下降,但 CABG 后下降幅度更大。
自 1994 年以来,与 CABG 相比,PCI 的比例显著增加。在同一时期,CABG 患者的风险调整住院死亡率下降幅度大于 PCI 患者。需要进一步研究以确定 PCI 和 CABG 比率在临床结果和资源利用方面的适宜性。