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多支血管病变且具有I类手术指征患者冠状动脉旁路移植手术下降趋势的决定因素

Determinants of the Downward Trend in Coronary Artery Bypass Graft Surgery Among Patients With Multivessel Disease and Class-I Indication for Surgery.

作者信息

Ali Jabar, Khan Fahad R, Khattak Safi, Ullah Hidayat, Ullah Rizwan, Lakhta Gul

机构信息

Cardiology/Interventional Cardiology, Lady Reading Hospital, Peshawar, PAK.

Cardiology, Lady Reading Hospital, Peshawar, PAK.

出版信息

Cureus. 2021 Mar 25;13(3):e14098. doi: 10.7759/cureus.14098.

Abstract

Introduction Coronary artery bypass graft (CABG) is the most effective coronary revascularization procedure, and it has been endorsed by many trials and studies over the years. However, due to CABG's immediate adverse effects, patients tend to prefer percutaneous coronary intervention (PCI) for coronary revascularization over it. This article focuses on the recent downtrend in CABG procedures for revascularization among patients for whom it is indicated. This study's main objective was to identify the factors responsible for the downtrend in patients undergoing CABG despite a clear indication for it in those with multivessel diseases. Methods This study was conducted at the Lady Reading Hospital, Peshawar, Pakistan, from August 1, 2020, to January 1, 2021. A total of 340 patients with a class-I indication (presence of conditions regarding which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective) for CABG were enrolled in the study. Data related to all the variables were collected from patients and hospital records through an adequately designed proforma. For analysis, we applied the chi-square test to elaborate on the data for information and point biserial correlation to rule out the effect of age and weight on CABG's downward trend. Results The mean age of the patients was 58.77 ±9.54 years; 65.88% were male, and 34.12% were female. Only 17.65% of the patients underwent CABG; 71.47% opted for medical treatment, and 9.41% underwent PCI. Out of the 280 patients who did not undergo CABG, 26.76% had financial issues; 23.82% were high-risk patients and hence refused surgeries by the surgeons; 20.59% of patients were not willing to undergo surgery; 7.94% were on the waiting list, and 3.24% had deranged renal function tests (RFTs). Conclusions A limited number of patients underwent revascularization therapy even though they had clear indications for CABG. The high-risk status of patients, patients' unwillingness, and the cost of the procedure were the primary reasons behind the downtrend in CABG procedures among patients with a clear indication for the same.

摘要

引言

冠状动脉旁路移植术(CABG)是最有效的冠状动脉血运重建手术,多年来已得到许多试验和研究的认可。然而,由于CABG的直接不良反应,患者在冠状动脉血运重建方面往往更倾向于经皮冠状动脉介入治疗(PCI)而非CABG。本文重点关注了在有适应证的患者中,CABG血运重建手术近期的下降趋势。本研究的主要目的是确定尽管多支血管疾病患者有明确的CABG适应证,但接受CABG手术的患者数量下降的原因。

方法

本研究于2020年8月1日至2021年1月1日在巴基斯坦白沙瓦的莱迪·里德医院进行。共有340例有CABG I类适应证(存在有证据和/或普遍共识表明某种特定手术或治疗有益、有用且有效的情况)的患者纳入研究。通过精心设计的表格从患者和医院记录中收集与所有变量相关的数据。为进行分析,我们应用卡方检验来详细阐述数据信息,并应用点二列相关分析以排除年龄和体重对CABG下降趋势的影响。

结果

患者的平均年龄为58.77±9.54岁;男性占65.88%,女性占34.12%。仅17.65%的患者接受了CABG;71.47%选择了药物治疗,9.41%接受了PCI。在未接受CABG的280例患者中,26.76%有经济问题;23.82%是高危患者,因此外科医生拒绝为其手术;20.59%的患者不愿意接受手术;7.94%在等待名单上,3.24%的患者肾功能检查结果异常。

结论

尽管有明确的CABG适应证,但接受血运重建治疗的患者数量有限。患者的高危状态、患者的不愿意以及手术费用是有明确适应证的患者中CABG手术下降趋势的主要原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d7/8065682/56964914c747/cureus-0013-00000014098-i01.jpg

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