[Isotretinoin, depression and medias].

Acne is a frequent disease with a strong impact upon quality of life. The most effective treatment of severe acne is isotretinoin. Cases of suicid have been reported during isotretinoin treatments in adolescents and were mediatised. Now a day, the link between isotretinoin intake and psychiatric troubles is not established at populational level. The pressure of public and medias led the French Drug Agency to send a letter to health professionals to summarize the scientific question. An explanative video is on line on the website of the French Society of Dermatology www.dermato-info.fr. This video summarizes the state of the art concerning the context of isotretinoin for public, dermatologists and other physicians To summarize isotretinoin is the drug for severe acne in case of failure of first line classical treatment. Dermatologists must stay the first line prescribers reminding that adolescence is a fragile period.