Department of Molecular Biology, Centre for mRNP Biogenesis and Metabolism, CF Møllers Allé 3, Building 1130, Aarhus University, 8000 Aarhus, Denmark.
Mol Cell. 2010 Nov 24;40(4):503-5. doi: 10.1016/j.molcel.2010.11.019.
Maturation of mRNA termini occurs during transcription and can be aided by pausing of RNA polymerase II (RNAPII). In this issue of Molecular Cell, two groups now demonstrate that RNAPII pausing may also assist cotranscriptional splicing in S. cerevisiae.
mRNA 末端的成熟发生在转录过程中，可以通过 RNA 聚合酶 II（RNAPII）的暂停来辅助。在本期《分子细胞》中，两个研究小组现在证明，RNAPII 暂停也可能有助于酿酒酵母的共转录剪接。
