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Multimodal optical imaging for simultaneous in-vivo morphological and biochemical characterization of oral epithelial cancer.

作者信息

Shrestha Sebina, Park Jesung, Pande Paritosh, Applegate Brian E, Jo Javier A

机构信息

Department of Biomedical Engineering at Texas A&M University, College Station, TX, USA.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:1970-3. doi: 10.1109/IEMBS.2010.5627569.

DOI:10.1109/IEMBS.2010.5627569
PMID:21096785
Abstract

Early detection of cancer is key to reducing morbidity and mortality. Morphological and chemical biomarkers presage the transition from normal to cancerous tissue. We have developed a noninvasive imaging system incorporating optical coherence tomography and fluorescence lifetime imaging to acquire both sets of biomarkers. Here we report early favorable results from an animal study designed to measure the capacity of this approach for early diagnosis of oral cancer.

摘要

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