光学相干断层扫描在口腔恶性肿瘤早期诊断中的应用潜力。
Potential of optical coherence tomography for early diagnosis of oral malignancies.
机构信息
Beckman Laser Institute, 1002 Health Sciences Road East, University of California, Irvine, CA 92612, USA.
出版信息
Expert Rev Anticancer Ther. 2010 Mar;10(3):321-9. doi: 10.1586/era.09.191.
Abstract
With nearly 1,500,000 new patients diagnosed every year in the USA, cancer poses a considerable challenge to healthcare today. Oral cancer is responsible for a sizeable portion of deaths due to cancer, primarily because it is diagnosed at a late stage when the prognosis is poor. Current methods for diagnosing oral cancer need to be augmented by better early detection, monitoring and screening modalities. A new approach is needed that provides real-time, accurate, noninvasive diagnosis. The results of early clinical trials using in vivo optical coherence tomography for the diagnosis of oral dysplasia and malignancy are encouraging.
摘要
在美国，每年有近 150 万新患者被诊断出患有癌症，这对当今的医疗保健构成了相当大的挑战。口腔癌是癌症导致死亡的主要原因之一，主要是因为它在预后较差的晚期才被诊断出来。目前诊断口腔癌的方法需要通过更好的早期检测、监测和筛查手段来加以补充。需要一种新的方法来提供实时、准确、非侵入性的诊断。使用体内光学相干断层扫描技术对口腔发育异常和恶性肿瘤进行早期诊断的临床试验结果令人鼓舞。
相似文献
1
Potential of optical coherence tomography for early diagnosis of oral malignancies.光学相干断层扫描在口腔恶性肿瘤早期诊断中的应用潜力。
Expert Rev Anticancer Ther. 2010 Mar;10(3):321-9. doi: 10.1586/era.09.191.
2
Oral Cancer Update: 2017.
Northwest Dent. 2017 Jan;96(1):21-3, 25-7.
3
Early detection of premalignant lesions and oral cancer.癌前病变和口腔癌的早期检测。
Otolaryngol Clin North Am. 2011 Feb;44(1):221-9, vii. doi: 10.1016/j.otc.2010.10.002.
4
An update on the clinical pathology of oral precancer and cancer.口腔癌前病变和癌症临床病理学的最新进展。
Dent Update. 2013 Mar;40(2):120-2, 125-6. doi: 10.12968/denu.2013.40.2.120.
5
[Optical coherence tomography in the evaluation of the oral cavity mucosa. Part II. Benign and malignant diseases].[光学相干断层扫描在口腔黏膜评估中的应用。第二部分。良性和恶性疾病]
Stomatologiia (Mosk). 2004;83(4):25-32.
6
Exciting new advances in oral cancer diagnosis: avenues to early detection.口腔癌诊断的令人振奋的新进展：早期检测途径
Head Neck Oncol. 2011 Jul 28;3:33. doi: 10.1186/1758-3284-3-33.
7
Screening for Oral Cavity Cancer: A 1-year Experience of a Regional Hospital in Taiwan.口腔癌筛查：台湾一家地区医院的一年经验
JNMA J Nepal Med Assoc. 2014 Jul-Sep;52(195):902-6.
8
In vitro examination of suspicious oral lesions using optical coherence tomography.使用光学相干断层扫描技术对可疑口腔病变进行体外检查。
Br J Oral Maxillofac Surg. 2010 Jan;48(1):18-25. doi: 10.1016/j.bjoms.2009.04.019. Epub 2009 Sep 1.
9
[Screening and diagnosis of precancerous oral mucosa lesions].[口腔黏膜癌前病变的筛查与诊断]
Rev Stomatol Chir Maxillofac. 2010 Sep;111(4):203-7. doi: 10.1016/j.stomax.2010.07.005. Epub 2010 Aug 24.
10
[Current concepts in diagnosis and treatment of oral malignant tumors].[口腔恶性肿瘤诊断与治疗的当前概念]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Sep;54(9):1083-8. doi: 10.1007/s00103-011-1334-x.
引用本文的文献
1
Integration of the fluorescence based portable device with the AI tools for the real-time monitoring of oral mucosal lesions.将基于荧光的便携式设备与人工智能工具集成，用于口腔黏膜病变的实时监测。
Sci Rep. 2025 Mar 25;15(1):10222. doi: 10.1038/s41598-025-94676-w.
2
Quantum leap in the diagnosis of oral potentially malignant disorders - A review of literature.口腔潜在恶性疾病诊断的重大进展——文献综述
Natl J Maxillofac Surg. 2024 Sep-Dec;15(3):360-366. doi: 10.4103/njms.njms_132_23. Epub 2024 Nov 16.
3
High-speed, long-range and wide-field OCT for in vivo 3D imaging of the oral cavity achieved by a 600 kHz swept source laser.通过600kHz扫频光源激光实现的用于口腔体内三维成像的高速、远程和宽视野光学相干断层扫描
Biomed Opt Express. 2024 Jun 27;15(7):4365-4380. doi: 10.1364/BOE.528287. eCollection 2024 Jul 1.
4
Evaluation of Usage of Different Diagnostic Aids for Oral Cancer by Oral and Maxillofacial Surgeons: An Original Research.口腔颌面外科医生对不同口腔癌诊断辅助工具使用情况的评估：一项原创研究。
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S272-S275. doi: 10.4103/jpbs.jpbs_489_23. Epub 2024 Feb 29.
5
Detection of oral mucosal lesions by the fluorescence spectroscopy and classification of cancerous stages by support vector machine.荧光光谱法检测口腔黏膜病变及支持向量机对癌变阶段的分类。
Lasers Med Sci. 2024 Jan 19;39(1):42. doi: 10.1007/s10103-024-03995-3.
6
Human Saliva as a Substitute Diagnostic Medium for the Detection of Oral Lesions Using the Stokes Shift Spectroscopy: Discrimination among the Groups by Multivariate Analysis Methods.利用斯托克斯位移光谱学，以人唾液作为替代诊断介质检测口腔病变：通过多元分析方法对各组进行区分。
Asian Pac J Cancer Prev. 2023 Nov 1;24(11):3757-3763. doi: 10.31557/APJCP.2023.24.11.3757.
7
Tumour Necrosis Factor Alpha (TNF-α) and Oral Squamous Cell Carcinoma.肿瘤坏死因子α（TNF-α）与口腔鳞状细胞癌
Cancers (Basel). 2023 Mar 19;15(6):1841. doi: 10.3390/cancers15061841.
8
In-vivo Testing of Oral Mucosal Lesions with an In-house Developed Portable Imaging Device and Comparison with Spectroscopy Results.体内测试口腔黏膜病变的便携式成像设备及其与光谱学结果的比较。
J Fluoresc. 2023 Jul;33(4):1375-1383. doi: 10.1007/s10895-023-03152-z. Epub 2023 Jan 26.
9
Optical coherence tomography imaging of melanoma skin cancer.黑色素瘤皮肤癌的光学相干断层扫描成像
Lasers Med Sci. 2019 Mar;34(2):411-420. doi: 10.1007/s10103-018-2696-1. Epub 2018 Dec 11.
10
Optical techniques for cervical neoplasia detection.用于宫颈癌前病变检测的光学技术。
Beilstein J Nanotechnol. 2017 Sep 6;8:1844-1862. doi: 10.3762/bjnano.8.186. eCollection 2017.
本文引用的文献
1
Optical coherence tomography.光学相干断层扫描
J Biomed Opt. 1996 Apr;1(2):157-73. doi: 10.1117/12.231361.
2
Optical coherence tomography as a method for studying sutureless microincisional vitrectomy sclerotomies.
Am J Ophthalmol. 2009 Aug;148(2):321-2; author reply 322-3. doi: 10.1016/j.ajo.2009.04.013.
3
Optical coherence tomography patterns of stent restenosis.支架再狭窄的光学相干断层扫描模式
Am Heart J. 2009 Aug;158(2):284-93. doi: 10.1016/j.ahj.2009.06.004.
4
Intraductal optical coherence tomography during endoscopic retrograde cholangiopancreatography for investigation of biliary strictures.内镜逆行胰胆管造影术中的导管内光学相干断层扫描用于胆管狭窄的研究。
Endoscopy. 2009 Aug;41(8):696-701. doi: 10.1055/s-0029-1214950. Epub 2009 Jul 17.
5
New and current clinical imaging techniques to study chronic obstructive pulmonary disease.用于研究慢性阻塞性肺疾病的新型及现有临床成像技术。
Am J Respir Crit Care Med. 2009 Oct 1;180(7):588-97. doi: 10.1164/rccm.200901-0159PP. Epub 2009 Jul 16.
6
Reconstruction of in-vivo optical properties for human prostate using interstitial diffuse optical tomography.利用间质扩散光学断层扫描重建人体前列腺的体内光学特性。
Opt Express. 2009 Jul 6;17(14):11665-72. doi: 10.1364/oe.17.011665.
7
Optical coherence tomography in children with coeliac disease.患有乳糜泻儿童的光学相干断层扫描
Dig Liver Dis. 2009 Sep;41(9):630-1. doi: 10.1016/j.dld.2009.05.017. Epub 2009 Jul 2.
8
Quantifying tracheobronchial tree dimensions: methods, limitations and emerging techniques.量化气管支气管树的尺寸：方法、局限性及新兴技术
Eur Respir J. 2009 Jul;34(1):42-55. doi: 10.1183/09031936.00020408.
9
OCT imaging of skin cancer and other dermatological diseases.皮肤癌及其他皮肤病的光学相干断层扫描成像
J Biophotonics. 2009 Jul;2(6-7):442-51. doi: 10.1002/jbio.200910020.
10
In vivo diagnosis of oral dysplasia and malignancy using optical coherence tomography: preliminary studies in 50 patients.使用光学相干断层扫描进行口腔发育异常和恶性肿瘤的体内诊断：50例患者的初步研究
Lasers Surg Med. 2009 Jul;41(5):353-7. doi: 10.1002/lsm.20773.
Zotero 插件