光学相干断层扫描在口腔恶性肿瘤早期诊断中的应用潜力。
Potential of optical coherence tomography for early diagnosis of oral malignancies.
机构信息
Beckman Laser Institute, 1002 Health Sciences Road East, University of California, Irvine, CA 92612, USA.
出版信息
Expert Rev Anticancer Ther. 2010 Mar;10(3):321-9. doi: 10.1586/era.09.191.
Abstract
With nearly 1,500,000 new patients diagnosed every year in the USA, cancer poses a considerable challenge to healthcare today. Oral cancer is responsible for a sizeable portion of deaths due to cancer, primarily because it is diagnosed at a late stage when the prognosis is poor. Current methods for diagnosing oral cancer need to be augmented by better early detection, monitoring and screening modalities. A new approach is needed that provides real-time, accurate, noninvasive diagnosis. The results of early clinical trials using in vivo optical coherence tomography for the diagnosis of oral dysplasia and malignancy are encouraging.
摘要
在美国，每年有近 150 万新患者被诊断出患有癌症，这对当今的医疗保健构成了相当大的挑战。口腔癌是癌症导致死亡的主要原因之一，主要是因为它在预后较差的晚期才被诊断出来。目前诊断口腔癌的方法需要通过更好的早期检测、监测和筛查手段来加以补充。需要一种新的方法来提供实时、准确、非侵入性的诊断。使用体内光学相干断层扫描技术对口腔发育异常和恶性肿瘤进行早期诊断的临床试验结果令人鼓舞。
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