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Lack of interference by sorbitol with aminopyrine breath test.

作者信息

Ramin V C, Bircher J

机构信息

Division of Clinical Pharmacology, University of Göttingen, Federal Republic of Germany.

出版信息

Eur J Clin Pharmacol. 1990;38(1):87-9. doi: 10.1007/BF00314811.

DOI:10.1007/BF00314811
PMID:2109699
Abstract

The effect of sorbitol on the aminopyrine breath test was investigated in 13 patients with various liver diseases given a bolus dose of sorbitol 20 mg.kg-1 i.v. 30 min after 14C-aminopyrine and 13 patients without the sorbitol bolus who also underwent an aminopyrine breath test. The time course of 14CO2 exhalation after the bolus of sorbitol did not differ from that in the control group.

摘要

相似文献

1
Lack of interference by sorbitol with aminopyrine breath test.
Eur J Clin Pharmacol. 1990;38(1):87-9. doi: 10.1007/BF00314811.
2
Quantitative assessment of hepatic function by breath analysis after oral administration of (14C)aminopyrine.口服（14C）氨基比林后通过呼吸分析对肝功能进行定量评估。
Ann Intern Med. 1975 Nov;83(5):632-8. doi: 10.7326/0003-4819-83-5-632.
3
Assessment of drug metabolism in hepatic disease: comparison of plasma kinetics of oral cyclobarbital and the intravenous aminopyrine breath test.肝病中药物代谢的评估：口服环己巴比妥血浆动力学与静脉注射氨基比林呼吸试验的比较
Eur J Clin Pharmacol. 1984;26(1):95-101. doi: 10.1007/BF00546715.
4
14C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease.
Digestion. 1978;17(5):410-8. doi: 10.1159/000198144.
5
Limited usefulness of the breath test in evaluation of drug metabolism: a study in human oral contraceptive users treated with dimethylaminoantipyrine and diazepam.呼气试验在药物代谢评估中的作用有限：一项针对服用二甲氨基安替比林和地西泮的口服避孕药使用者的研究。
Hepatogastroenterology. 1980 Apr;27(2):104-8.
6
Abnormal aminopyrine metabolism in patients with hepatic neoplasm. Detection by breath test.
JAMA. 1976 Oct 4;236(14):1587-90.
7
Plasma levels of parent drug and metabolites in the intravenous aminopyrine breath test.静脉注射氨基比林呼气试验中母体药物和代谢物的血浆水平。
Eur J Clin Pharmacol. 1982;21(6):521-8. doi: 10.1007/BF00542049.
8
Breath 14CO2 after intravenous administration of [14C]aminopyrine in liver diseases.肝脏疾病患者静脉注射[14C]氨基比林后的呼气14CO2 。
Dig Dis Sci. 1982 Jan;27(1):49-56. doi: 10.1007/BF01308121.
9
Dose dependence of the 14C-aminopyrine breath test. Intrasubject comparison of tracer and pharmacological doses.14C-氨基比林呼气试验的剂量依赖性。示踪剂剂量与药理剂量的受试者内比较。
Eur J Clin Pharmacol. 1977 Nov 14;12(3):229-33. doi: 10.1007/BF00609866.
10
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.口服14C-氨基比林后通过呼吸分析评估人体中氨基比林的代谢。苯巴比妥、双硫仑和门脉性肝硬化的影响。
N Engl J Med. 1974 Dec 26;291(26):1384-8. doi: 10.1056/NEJM197412262912605.

本文引用的文献

1
Stimulation of p-nitroanisole O-demethylation in perfused livers by xylitol and sorbitol.木糖醇和山梨醇对灌流肝脏中对硝基苯甲醚 O-脱甲基化的刺激作用。
Biochem Pharmacol. 1980 Mar 1;29(5):813-9. doi: 10.1016/0006-2952(80)90562-6.
2
Determination of the hepatic elimination capacity (Lm) of galactose by single injection.通过单次注射测定半乳糖的肝脏清除能力（Lm）。
Scand J Clin Lab Invest Suppl. 1966;18:118-25.
3
Steady-state extrarenal sorbitol clearance as a measure of hepatic plasma flow.
Gastroenterology. 1988 Sep;95(3):749-59. doi: 10.1016/s0016-5085(88)80024-6.
4
The 30-minute aminopyrine breath test: optimization of sampling times after intravenous administration of 14C-aminopyrine.
Digestion. 1988;39(4):241-50. doi: 10.1159/000199632.
5
[The aminopyrine respiratory test under the acute effect of ethanol. Evaluation of a new method for the measurement of microsomal functions of the liver].[乙醇急性作用下的氨基比林呼吸试验。一种测量肝脏微粒体功能的新方法的评估]
Schweiz Med Wochenschr. 1977 Feb 19;107(7):231-5.