Miller Kai J, Hebb Adam O, Hermes Dora, den Nijs Marcel, Ojemann Jeffrey G, Rao Rajesh N P
University of Washington, Seattle, WA 98195, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:6015-8. doi: 10.1109/IEMBS.2010.5627597.
Electrocorticographic recording is now being used in a wide variety of experimental settings. We present a simple method which can be used to estimate electrode position with respect to brain gyral anatomy using a pre-implantation MRI and post-implantation coronal and sagittal x-rays. It is semi-automated, with the user manually rotating and scaling an x-ray to fit brain outline, identifying threshold values for brain surface rendering, and clicking on electrodes on an x-ray. Electrode positions can be rapidly identified and rendered in about 20 minutes from start to finish. This approach is useful when the MRI quality is poor, there is no quality CT, but one would like to understand the relationship between experimental result and brain anatomy.
目前，脑皮层电图记录正被广泛应用于各种实验环境中。我们提出了一种简单的方法，该方法可利用植入前的磁共振成像（MRI）以及植入后的冠状位和矢状位X射线来估计电极相对于脑回解剖结构的位置。它是半自动的，用户需手动旋转和缩放X射线以使其符合脑轮廓，确定脑表面渲染的阈值，并在X射线上点击电极。从开始到结束，电极位置大约能在20分钟内快速确定并呈现出来。当MRI质量较差且没有高质量的计算机断层扫描（CT），但又想了解实验结果与脑解剖结构之间的关系时，这种方法很有用。
