Burton Mary Jane, Reilly Kathleen H, Penman Alan
University of Mississippi Medical Center, Jackson, Mississippi, USA.
J Health Care Poor Underserved. 2010 Nov;21(4):1194-202. doi: 10.1353/hpu.2010.0938.
Injection drug use (IDU) is the most commonly recognized risk factor for co-infection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). We examined risks for HIV/HCV co-infection in a population with a low rate of IDU.
A sample of 32 HIV/HCV co-infected patients and 79 HIV-infected patients were enrolled from two clinics in Mississippi. Patients completed an audio computer-assisted self-interview (ACASI) assessing risks for infection with both viruses.
In a multivariable logistic regression model, greater age (p=.01), alcohol use (p=.02), history of incarceration (p=.04), and blood transfusion prior to 1992 (p=.03) were independently associated with HIV/HCV co-infection.
Incarceration was significantly associated with HIV-HCV co-infection in our sample. Further examination is warranted to develop policies for HCV prevention and treatment within the prison system.
注射吸毒是最常见的同时感染人类免疫缺陷病毒（HIV）和丙型肝炎病毒（HCV）的危险因素。我们在一个注射吸毒率较低的人群中研究了HIV/HCV合并感染的风险。
从密西西比州的两家诊所招募了32例HIV/HCV合并感染患者和79例HIV感染患者。患者完成了一项音频计算机辅助自我访谈（ACASI），评估感染两种病毒的风险。
在多变量逻辑回归模型中，年龄较大（p = 0.01）、饮酒（p = 0.02）、有监禁史（p = 0.04）和1992年以前接受输血（p = 0.03）与HIV/HCV合并感染独立相关。
在我们的样本中，监禁与HIV-HCV合并感染显著相关。有必要进一步研究，以制定监狱系统内丙型肝炎预防和治疗的政策。
